Goat Polyclonal IGHG1 antibody - conjugated to FITC. Suitable for Flow Cyt, IHC-Fr and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Full Length Protein corresponding to Human Immunoglobulin heavy constant gamma 1.
IgG
Goat
FITC
Ex: 495nm, Em: 519nm
pH: 7.5
Constituents: 50% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.164% Sodium phosphate
Liquid
Polyclonal
| Flow Cyt | IHC-Fr | |
|---|---|---|
| Human | Expected | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes ab37394 - Goat polyclonal IgG, is suitable for use as an isotype control with this antibody. |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
Select an associated product type
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:22158414, PubMed:20176268). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268).
Immunoglobulin heavy constant gamma 1, Ig gamma-1 chain C region, Ig gamma-1 chain C region EU, Ig gamma-1 chain C region KOL, Ig gamma-1 chain C region NIE, IGHG1
Goat Polyclonal IGHG1 antibody - conjugated to FITC. Suitable for Flow Cyt, IHC-Fr and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Full Length Protein corresponding to Human Immunoglobulin heavy constant gamma 1.
IgG
Goat
FITC
Ex: 495nm, Em: 519nm
pH: 7.5
Constituents: 50% Glycerol (glycerin, glycerine), 0.58% Sodium chloride, 0.164% Sodium phosphate
Liquid
Polyclonal
Affinity purification Immunogen
Low background fluorescence of normal tissue in contrast to cases of autoimmune disease, deposited immunoglobulin IgG. No cross reactivity with albumin fractions of human serum. No cross reactivity with albumin fractions of animal species.
From the crude polyclonal the crossreactive antibodies were extracted by incubation with Sepharose bound human IgA and IgM. Specific antibodies were absorbed by incubation with Sepharose bound human IgG. Specific antibodies were eluted by acidic buffer at pH 2.5 followed by neutralisation and dialysis. After repeated binding with immobilized human IgG a minimum of 65% protein bound.
Blue Ice
+4°C
The purified polyclonal was conjugated to fluorescein isothiocyanate isomer I followed by gel filtation and ion exchange chromatography to clear unbound conjugate. F/P ratio: 4-6 mol Fluorescein per 1 mol of goat IgG.
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