AB210332

FITC Anti-IL-2 Receptor alpha antibody [PC61.5]

Name: FITC Anti-IL-2 Receptor alpha antibody [PC61.5] (ab210332) | Abcam
Brand: Abcam Limited
SKU: AB210332
Price: 230 USD
Availability: InStock

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(5 Publications)

Rat Monoclonal IL2RA antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Mouse samples. Cited in 5 publications.

View Alternative Names

CD25, Il2r, Il2ra, Interleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, p55

1 Images

Flow Cytometry - FITC Anti-IL-2 Receptor alpha antibody [PC61.5] (AB210332)

Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-IL-2 Receptor alpha antibody [PC61.5] (AB210332)

Flow cytometric analysis of mouse C57Bl/6 spleen cells stained with APC Anti-Mouse IL-2 Receptor alpha antibody and ab210332 at 0.125 μg (right panel) or FITC Rat IgG1 isotype control at 0.125 μg (left panel).

660 APC

APC Anti-IL-2 Receptor alpha antibody [PC61.5]
778 PE/Cy7®

PE/Cy7® Anti-IL-2 Receptor alpha antibody [PC61.5]
695 PerCP/Cy5.5®

PerCP/Cy5.5® Anti-IL-2 Receptor alpha antibody [PC61.5]
450 violetFluor™ 450

violetFluor™ 450 Anti-IL-2 Receptor alpha antibody [PC61.5]

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

PC61.5

Isotype

IgG1

Light chain type

lambda

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

Reacts with

Mouse

Applications

Flow Cyt

applications

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Use at 0.125 μg.</p>" } } }

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Product details

ab210332 is used as a marker for T cells, B cells and dendritic cell subsets. Expression of CD25, CD4 and the transcription factor Foxp3 is regarded as a phenotypic signature for Treg cells. As such, this antibody is widely used to distinguish Treg cells from naïve or conventional T cells which are CD25-. This clone has also been reported for depletion of Treg cells in vivo.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Purification notes

ab210332 was purified from tissue culture supernatant and conjugated under optimal conditions, with unreacted dye removed from the preparation.

Storage buffer

pH: 7.2 Preservative: 0.09% Sodium azide Constituents: 0.87% Sodium chloride, 0.12% Sodium dihydrogen phosphate, 0.1% Gelatin

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

+4°C

Storage information

Store in the dark

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.

See full target information Il2ra

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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Histology and histopathology 39:511-523 PubMed37728155

2023

E2F1-EP300 co-activator complex potentiates immune escape in nasopharyngeal carcinoma through the mediation of MELK.

Applications

Unspecified application

Species

Unspecified reactive species

Qiang Wang,Qi Yu,Yueyang Liu

Advances in cancer biology - metastasis 7: PubMed37593105

2023

Benzophenone-3 exposure alters composition of tumor infiltrating immune cells and increases lung seeding of 4T1 breast cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Stephanie M Morin,Kelly J Gregory,Brenda Medeiros,Tigist Terefe,Reyhane Hoshyar,Ahmed Alhusseiny,Shiuan Chen,Richard C Schwartz,D Joseph Jerry,Laura N Vandenberg,Sallie S Schneider

Nephron 146:528-538 PubMed35176745

2022

Losartan Attenuates Atherosclerosis in Uremic Mice by Regulating Treg/Th17 Balance via Mediating PTEN/PI3K/Akt Pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Shanzhai Wei,Jie Sun,Yibei Li,Kangchun Xu,Man Wang,Yilai Zhang

Journal of gastroenterology and hepatology 37:154-163 PubMed34734434

2021

CD155/TIGIT signaling regulates the effector function of tumor-infiltrating CD8+ T cell by NF-κB pathway in colorectal cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Shanshan Li,Jihu Ding,Ying Wang,Xianling Wang,Lin Lv

Cancer cell international 21:58 PubMed33468159

2021

IRF4 overexpression promotes the transdifferentiation of tregs into macrophage-like cells to inhibit the development of colon cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jiwei Wang,Song Li,Honglang Li,Xiaoshuang Zhou,Huabin Wen,Bin Lai

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

FITC Anti-IL-2 Receptor alpha antibody [PC61.5]

Flow Cytometry - FITC Anti-IL-2 Receptor alpha antibody [PC61.5] (AB210332)

Related conjugates and formulations (4)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

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Reactivity data

Product details

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Storage information

Product protocols

Target data

Publications (5)

Product promise