Mouse Monoclonal IL-4 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Pig, Dog, Mink, Dolphin, Horse, Cow, Goat, Sheep samples.
Preservative: 0.09% Sodium azide
Constituents: 98% PBS, 1% BSA
| Flow Cyt | |
|---|---|
| Cow | Expected |
| Dog | Expected |
| Dolphin | Expected |
| Goat | Expected |
| Horse | Expected |
| Mink | Expected |
| Pig | Expected |
| Sheep | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Pig | Dilution info - | Notes Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Species Dog | Dilution info - | Notes Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Species Mink | Dilution info - | Notes Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Species Dolphin | Dilution info - | Notes Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Species Horse | Dilution info - | Notes Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Species Cow | Dilution info - | Notes Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Species Goat | Dilution info - | Notes Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
Species Sheep | Dilution info - | Notes Membrane permeabilization is required for this application. ab91362 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
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Cytokine secreted primarily by mast cells, T-cells, eosinophils, and basophils that plays a role in regulating antibody production, hematopoiesis and inflammation, and the development of effector T-cell responses (PubMed:1993171, PubMed:3016727). Induces the expression of class II MHC molecules on resting B-cells. Enhances both secretion and cell surface expression of IgE and IgG1 (PubMed:1993171). Regulates also the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (PubMed:2521231). Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4. In addition, plays a critical role in higher functions of the normal brain, such as memory and learning (By similarity). Upon binding to IL4, IL4R receptor dimerizes either with the common IL2R gamma chain/IL2RG to produce the type 1 signaling complex, located mainly on hematopoietic cells, or with the IL13RA1 to produce the type 2 complex, which is expressed also on nonhematopoietic cells (PubMed:10219247, PubMed:11526337, PubMed:18243101). Engagement of both types of receptors initiates JAK3 and to a lower extend JAK1 phosphorylation leading to activation of the signal transducer and activator of transcription 6/STAT6 (PubMed:7721895).
Interleukin-4, IL-4, B-cell stimulatory factor 1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra, BSF-1, IL4
Mouse Monoclonal IL-4 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Pig, Dog, Mink, Dolphin, Horse, Cow, Goat, Sheep samples.
Preservative: 0.09% Sodium azide
Constituents: 98% PBS, 1% BSA
ab186716 was prepared by affinity chromatography on Protein G from tissue culture supernatant.
Spleen cells from immunised BALB/c mice were fused with cells of the mouse SP2/0 myeloma cell line.
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