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AB326494

FITC Anti-IL3RA/CD123 antibody [6H6]

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Mouse Monoclonal IL3RA/CD123 antibody - conjugated to FITC. Suitable for Flow Cyt and reacts with Human samples.

View Alternative Names

CD123, IL3R, IL3RA, Interleukin-3 receptor subunit alpha, IL-3 receptor subunit alpha, IL-3R subunit alpha, IL-3R-alpha, IL-3RA

1 Images
Flow Cytometry - FITC Anti-IL3RA/CD123 antibody [6H6] (AB326494)
  • Flow Cyt

Supplier Data

Flow Cytometry - FITC Anti-IL3RA/CD123 antibody [6H6] (AB326494)

Flow cytometry analysis (surface staining) of human peripheral blood with ab326494.

  • Unconjugated

    Anti-IL3RA/CD123 antibody [6H6]

  • 660 APC

    APC Anti-IL3RA/CD123 antibody [6H6]

  • 660 APC

    APC Anti-IL3RA/CD123 antibody [6H6]

  • 723 Alexa Fluor® 700

    Alexa Fluor® 700 Anti-IL3RA/CD123 antibody [6H6]

  • Biotin

    Biotin Anti-IL3RA/CD123 antibody [6H6]

  • 519 FITC

    FITC Anti-IL3RA/CD123 antibody [6H6]

  • 578 PE

    PE Anti-IL3RA/CD123 antibody [6H6]

  • 578 PE

    PE Anti-IL3RA/CD123 antibody [6H6]

  • 667 PE/Cy5®

    PE/Cy5® Anti-IL3RA/CD123 antibody [6H6]

  • 778 PE/Cy7®

    PE/Cy7® Anti-IL3RA/CD123 antibody [6H6]

  • 695 PerCP/Cy5.5®

    PerCP/Cy5.5® Anti-IL3RA/CD123 antibody [6H6]

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

6H6

Isotype

IgG1

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Specificity

The mouse monoclonal antibody 6H6 recognizes an extracellular epitope of CD123 (interleukin 3 receptor alpha), a 60-70 kDa transmembrane protein expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μl reagent / 100 μl of whole blood or 10^6 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Size-exclusion chromatography
Purification notes
Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Storage buffer
pH: 7.4 Preservative: 0.098% Sodium azide Constituents: PBS, 0.2% BSA
Shipped at conditions
Ambient - Can Ship with Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C
Storage information
Do Not Freeze|Store in the dark
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells (PubMed : 10527461). Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program (By similarity).
See full target information IL3RA
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Product promise

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