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AB69467

FITC Anti-Klebsiella spp antibody

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(1 Publication)

Rabbit Polyclonal Klebsiella spp antibody - conjugated to FITC. Suitable for ICC/IF, IHC-Fr and reacts with Klebsiella pneumoniae samples. Cited in 1 publication. Immunogen corresponding to Cell preparation containing Klebsiella spp protein.

View Alternative Names

Klebsiella

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Klebsiella pneumoniae

Applications

ICC/IF, IHC-Fr

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

ab69467 reacts with Klebsiella sp. in bacterial and infected tissue samples.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Klebsiella pneumoniae": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1/10", "ICCIF-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "1/10 - 1/50", "IHCFr-species-notes": "<p>Fix with Acetone.</p>" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Klebsiella spp also known as Klebsiella species refer to a group of non-motile Gram-negative bacteria often present in various environments like soil water and plants. The cells of Klebsiella species possess a polysaccharide capsule that is an important virulence factor contributing to their pathogenic potential by protecting against phagocytosis and antimicrobial substances. They exhibit a rod-shaped morphology with a size measuring approximately 1-2 microns in length. Klebsiella spp commonly colonizes the human gastrointestinal tract and respiratory system where they can coexist without causing harm under normal circumstances.
Biological function summary

This group of bacteria functions as opportunistic pathogens often forming biofilms that contribute to their resilience and pathogenicity. Klebsiella spp play roles in nitrogen cycling as they can fix atmospheric nitrogen into ammonia benefiting their surrounding environments. This ability links them to a multi-enzyme complex facilitating processes important for nitrogen utilization and metabolism. The capsule and lipopolysaccharide layers they produce significantly enhance their survival and capability to cause infections by impeding the immune system.

Pathways

Klebsiella spp are involved in various microbial metabolic pathways notably those associated with nitrogen fixation and carbohydrate metabolism. They participate in denitrification impacting nitrogen availability in the environment and closely interact with other microbial species in these metabolic processes. Klebsiella species share interactions with proteins such as nitrogenase enzymes important for converting atmospheric nitrogen to a biologically usable form emphasizing their role in ecological and host-microbe interactions.

Klebsiella spp are associated with healthcare-associated infections like pneumonia and urinary tract infections. These bacteria frequently cause respiratory infections especially in immunocompromised individuals such as those with chronic lung disease or diabetes. They contribute to diseases by producing extended-spectrum beta-lactamases (ESBLs) enzymes that confer resistance to many beta-lactam antibiotics. Proteins like fimbriae enhance their ability to adhere to host tissues exacerbating their role in opportunistic infections.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Methods in molecular biology (Clifton, N.J.) 2071:371-409 PubMed31758463

2019

Methods for the Measurement of Early Events in Toxoplasma gondii Immunity in Mouse Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Catalina Alvarez,Ana Claudia Campos,Jonathan C Howard,Joana Loureiro,Urs Benedikt Müller,Ana Lina Rodrigues
View all publications

Product promise

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