JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB68950

FITC Anti-Staphylococcus aureus antibody

Be the first to review this product! Submit a review

|

(7 Publications)

Rabbit Polyclonal Staphylococcus aureus antibody - conjugated to FITC. Suitable for ICC/IF, IHC-Fr and reacts with Staphylococcus aureus samples. Cited in 7 publications. Immunogen corresponding to Cell preparation containing Staphylococcus aureus protein.

View Alternative Names

IgG binding protein A, Immunoglobulin G binding protein A

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

FITC

Excitation/Emission

Ex: 495nm, Em: 519nm

Carrier free

No

Reacts with

Staphylococcus aureus

Applications

IHC-Fr, ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Staphylococcus aureus": { "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }

Product details

This antibody reacts with Staphylococcus aureus in bacterial and infected tissue samples.

Properties and storage information

Form
Liquid
Purification technique
Proprietary technique
Storage buffer
pH: 7.2 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
+4°C

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Staphylococcus aureus also known as "aureus" or "staph" is a gram-positive bacterium with a molecular mass ranging around 2.8 million daltons. It is found mainly in the nasal passages and on the skin of humans. This bacterium has a thick peptidoglycan layer making it resistant to certain environmental pressures. The structure of its proteins like Protein A plays an important role in immune evasion. Staphylococcus aureus also expresses a variety of toxins and enzymes that aid in its survival and pathogenicity.
Biological function summary

Staphylococcus aureus acts as an opportunistic pathogen that can cause infections when the host's immune system is weakened. It is not part of a specific protein complex but utilizes a range of virulence factors to establish infections. The bacterium produces biofilms which provide a protective environment against host defenses and antimicrobial agents. Its ability to quickly adapt to different environments makes it a major cause of both nosocomial and community-acquired infections.

Pathways

The metabolic activities of Staphylococcus aureus are involved in two significant pathways: the peptidoglycan biosynthesis and the toxin production pathway. Peptidoglycan biosynthesis is essential for cell wall integrity while toxin production pathways lead to the synthesis of critical virulence factors like alpha-hemolysin. Key proteins involved in these pathways include PBP2a which is significant for methicillin resistance and hemolysins that damage host tissues.

Staphylococcus aureus is connected to skin infections and pneumonia. The bacterium is notorious for causing conditions such as MRSA (methicillin-resistant Staphylococcus aureus) infections which are challenging to treat due to antibiotic resistance. Protein A interaction with the Fc region of immunoglobulin contributes to the evasion of immune responses and chronic infection persistence. These properties make staph infections a significant concern in both hospital and community settings.

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Publications (7)

Recent publications for all applications. Explore the full list and refine your search

BMC microbiology 25:12 PubMed39799329

2025

Phagocytosis by macrophages decreases the radiance of bioluminescent Staphylococcus aureus.

Applications

Unspecified application

Species

Unspecified reactive species

Elles C Boonstra,Liliana Agresti,Henny C van der Mei,Paul C Jutte,Jelmer Sjollema

Regenerative biomaterials 10:rbad046 PubMed37287896

2023

A multifunctional nanocomposite hydrogel with controllable release behavior enhances bone regeneration.

Applications

Unspecified application

Species

Unspecified reactive species

Yingji Mao,Yiwen Zhang,Ying Wang,Tao Zhou,Bingxu Ma,Pinghui Zhou

PloS one 15:e0231276 PubMed32275737

2020

Boron doped silver-copper alloy nanoparticle targeting intracellular S. aureus in bone cells.

Applications

Unspecified application

Species

Unspecified reactive species

Tahir Abdulrehman,Shahnaz Qadri,Sini Skariah,Ali Sultan,Said Mansour,Jamil Azzi,Yousef Haik

Immunology 157:122-136 PubMed30773630

2019

Daily variation in macrophage phagocytosis is clock-independent and dispensable for cytokine production.

Applications

Unspecified application

Species

Unspecified reactive species

Sarah S Geiger,Annie M Curtis,Luke A J O'Neill,Richard M Siegel

Allergy 74:560-571 PubMed30269350

2018

Staphylococcus aureus from atopic dermatitis skin accumulates in the lysosomes of keratinocytes with induction of IL-1α secretion via TLR9.

Applications

Unspecified application

Species

Unspecified reactive species

Masaya Moriwaki,Kazumasa Iwamoto,Yoshie Niitsu,Ayako Matsushima,Yuhki Yanase,Junzo Hisatsune,Motoyuki Sugai,Michihiro Hide

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 24:657-68 PubMed27238250

2016

Ciprofloxacin-loaded keratin hydrogels reduce infection and support healing in a porcine partial-thickness thermal burn.

Applications

Unspecified application

Species

Unspecified reactive species

Daniel C Roy,Seth Tomblyn,Kameel M Isaac,Christine J Kowalczewski,David M Burmeister,Luke R Burnett,Robert J Christy

BMC research notes 9:216 PubMed27071769

2016

An optimized staining technique for the detection of Gram positive and Gram negative bacteria within tissue.

Applications

Unspecified application

Species

Unspecified reactive species

Sandra C Becerra,Daniel C Roy,Carlos J Sanchez,Robert J Christy,David M Burmeister
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com