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AB154023

Anti-FLRT2 antibody

3

(1 Review)

|

(5 Publications)

Rabbit Polyclonal FLRT2 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FLRT2 aa 50-300.

View Alternative Names

KIAA0405, UNQ232/PRO265, FLRT2, Leucine-rich repeat transmembrane protein FLRT2, Fibronectin-like domain-containing leucine-rich transmembrane protein 2

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FLRT2 antibody (AB154023)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FLRT2 antibody (AB154023)

Immunohistochemical analysis of paraffin-embedded Human Mahlarvu xenograft tissue labeling FLRT2 with ab154023 at 1/500 dilution.

Western blot - Anti-FLRT2 antibody (AB154023)
  • WB

Unknown

Western blot - Anti-FLRT2 antibody (AB154023)

7.5% SDS PAGE

All lanes:

Western blot - Anti-FLRT2 antibody (ab154023) at 1/1000 dilution

All lanes:

A431 whole cell lysate at 30 µg

Predicted band size: 74 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human FLRT2 aa 50-300. The exact immunogen used to generate this antibody is proprietary information.

O43155

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 20% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis.
See full target information FLRT2

Publications (5)

Recent publications for all applications. Explore the full list and refine your search

BMC cancer 24:1158 PubMed39289660

2024

UBE2T promotes stage I lung adenocarcinoma progression through PBX1 ubiquitination and PBX1/RORA regulation.

Applications

Unspecified application

Species

Unspecified reactive species

Yujie Deng,Xiaohui Chen,Xuzheng Chen,Chuanzhong Huang,Zhiguang Zhang,Zhenguo Xu,Xiurong Wang,Jiamin Wu,Li Li,Jun Song,Ruixiang Zhou

JCI insight 9: PubMed38587072

2024

FLRT2 prevents endothelial cell senescence and vascular aging by regulating the ITGB4/mTORC2/p53 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Hyun Jung Hwang,Donghee Kang,Jae-Ryong Kim,Joon Hyuk Choi,Ji-Kan Ryu,Allison B Herman,Young-Gyu Ko,Heon Joo Park,Myriam Gorospe,Jae-Seon Lee

Journal of cellular and molecular medicine 28:e17855 PubMed37480224

2023

FLRT2 suppresses bladder cancer progression through inducing ferroptosis.

Applications

Unspecified application

Species

Unspecified reactive species

Pengcheng Jiang,Jinzhuo Ning,Weimin Yu,Ting Rao,Yuan Ruan,Fan Cheng

Journal of orthopaedic surgery and research 18:320 PubMed37098630

2023

LncRNA ZFAS1 protects chondrocytes from IL-1β-induced apoptosis and extracellular matrix degradation via regulating miR-7-5p/FLRT2 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Jicheng Han,Zongjian Luo,Yifei Wang,Yantao Liang

iScience 26:106535 PubMed37123250

2023

Apicosome: Newly identified cell-type-specific organelle in mouse cochlear and vestibular hair cells.

Applications

Unspecified application

Species

Unspecified reactive species

Xiaofen Li,Qirui Zhao,Xiaojie Yu,Wenhan Cao,Yingyi Zhang,Wanying Feng,Liwen Jiang,David Z He,Robert Z Qi,Pingbo Huang
View all publications

Product promise

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