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AB223047

Anti-FLRT3 antibody

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(3 Publications)

Rabbit Polyclonal FLRT3 antibody. Suitable for WB, ICC/IF and reacts with Mouse, Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FLRT3 aa 200-300.

View Alternative Names

KIAA1469, UNQ856/PRO1865, FLRT3, Leucine-rich repeat transmembrane protein FLRT3, Fibronectin-like domain-containing leucine-rich transmembrane protein 3

1 Images
Immunocytochemistry/ Immunofluorescence - Anti-FLRT3 antibody (AB223047)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-FLRT3 antibody (AB223047)

HepG2 (human liver hepatocellular carcinoma cell line) cells stained for FLRT3 (green) using ab223047 at 1/100 dilution in ICC/IF, followed by Alexa Fluor® 488-conjugated Goat Anti-Rabbit IgG (H+L).

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human FLRT3 aa 200-300. The exact immunogen used to generate this antibody is proprietary information.

Q9NZU0

Reactivity data

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity > 95%
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Functions in cell-cell adhesion, cell migration and axon guidance, exerting an attractive or repulsive role depending on its interaction partners. Plays a role in the spatial organization of brain neurons. Plays a role in vascular development in the retina (By similarity). Plays a role in cell-cell adhesion via its interaction with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells (PubMed : 26235030). Interaction with the intracellular domain of ROBO1 mediates axon attraction towards cells expressing NTN1. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5B, and possibly also other UNC-5 family members (By similarity). Promotes neurite outgrowth (in vitro) (PubMed : 14706654). Mediates cell-cell contacts that promote an increase both in neurite number and in neurite length. Plays a role in the regulation of the density of glutamaergic synapses. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal morphogenesis during embryonic development, but not for normal embryonic patterning. Required for normal ventral closure, headfold fusion and definitive endoderm migration during embryonic development. Required for the formation of a normal basement membrane and the maintenance of a normal anterior visceral endoderm during embryonic development (By similarity).
See full target information FLRT3

Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Lung 203:39 PubMed40047936

2025

FLRT3 Overexpression Attenuates Ischemia-Reperfusion Induced Vascular Hyperpermeability and Lung Injury Through RND3.

Applications

Unspecified application

Species

Unspecified reactive species

Yongmei Cao,Shiyang Sheng,Yong Zhong,Jiawei Shang,Cui Jin,Qin Tan,Feng Ping,Weifeng Huang,Yongchao Liu,Yingchuan Li

Cell communication and signaling : CCS 22:560 PubMed39574183

2024

Exploiting potential molecular compounds for treating testicular seminoma by targeting immune related genes.

Applications

Unspecified application

Species

Unspecified reactive species

Yankang Cui,Xiaodie Zhou,Jing Zhang,Bo Fang,Jingping Ge,Hao Tang,Bianjiang Liu,Haowei He,Feng Xu,Xuejun Shang

Aging 16:3647-3673 PubMed38358909

2024

Comprehensive analysis of disulfidptosis-related genes: a prognosis model construction and tumor microenvironment characterization in clear cell renal cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Bocun Yi,Xifeng Wei,Dongze Liu,Liwei Jing,Shengxian Xu,Man Zhang,Zhengxin Liang,Ranlu Liu,Zhihong Zhang
View all publications

Product promise

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