AB57963

Anti-FMNL2 antibody [2B4]

Name: Anti-FMNL2 antibody [2B4] (ab57963) | Abcam
Brand: Abcam Limited
SKU: AB57963
Price: 650 USD
Availability: InStock

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(14 Publications)

Mouse Monoclonal FMNL2 antibody. Suitable for WB and reacts with Human samples. Cited in 14 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human FMNL2.

View Alternative Names

FHOD2, KIAA1902, FMNL2, Formin-like protein 2, Formin homology 2 domain-containing protein 2

1 Images

Unknown

Western blot - Anti-FMNL2 antibody [2B4] (AB57963)

FMNL2 antibody (ab57963) at 1ug/lane + IMR-32 cell lysate at 25ug/lane.

This image was generated using the ascites version of the product.

All lanes:

Western blot - Anti-FMNL2 antibody [2B4] (ab57963)

Predicted band size: 123 kDa

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Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

2B4

Isotype

IgG1

Light chain type

kappa

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Recombinant Full Length Protein corresponding to Human FMNL2.

Q96PY5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }

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Product details

This product was changed from ascites to tissue culture supernatant on 17/04/2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

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Properties and storage information

Form

Liquid

Purity

Tissue culture supernatant

Storage buffer

pH: 7.4

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics.

See full target information FMNL2

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Publications (14)

Recent publications for all applications. Explore the full list and refine your search

iScience 28:112623 PubMed40502699

2025

Direct Arp2/3-vinculin binding is required for pseudopod extension, but only on compliant substrates and in 3D.

Applications

Unspecified application

Species

Unspecified reactive species

Tadamoto Isogai,Kevin M Dean,Philippe Roudot,Evgenia V Azarova,Kushal Bhatt,Meghan K Driscoll,Shaina P Royer,Nikhil Mittal,Bo-Jui Chang,Sangyoon J Han,Reto Fiolka,Gaudenz Danuser

Science advances 9:eadd6495 PubMed36662867

2023

ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning.

Applications

Unspecified application

Species

Unspecified reactive species

Florian Fäßler,Manjunath G Javoor,Julia Datler,Hermann Döring,Florian W Hofer,Georgi Dimchev,Victor-Valentin Hodirnau,Jan Faix,Klemens Rottner,Florian K M Schur

Journal of cell science 135: PubMed35971979

2022

Lamellipodia-like actin networks in cells lacking WAVE regulatory complex.

Applications

Unspecified application

Species

Unspecified reactive species

Frieda Kage,Hermann Döring,Magdalena Mietkowska,Matthias Schaks,Franziska Grüner,Stephanie Stahnke,Anika Steffen,Mathias Müsken,Theresia E B Stradal,Klemens Rottner

Journal of oncology 2022:5075615 PubMed35646112

2022

circRNA TCFL5 Promote Esophageal Cancer Progression by Modulating M2 Macrophage Polarization via the miR-543-FMNL2 Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Chengbin Lin,Yong Xi,Hongyan Yu,Zheng Wang,Xiaohan Chen,Weiyu Shen

PLoS pathogens 17:e1010184 PubMed34962968

2021

Neisseria gonorrhoeae subverts formin-dependent actin polymerization to colonize human macrophages.

Applications

Unspecified application

Species

Unspecified reactive species

Stanimir S Ivanov,Reneau Castore,Maria Dolores Juarez Rodriguez,Magdalena Circu,Ana-Maria Dragoi

Cell host & microbe 29:1316-1332.e12 PubMed34237247

2021

Global mapping of Salmonella enterica-host protein-protein interactions during infection.

Applications

Unspecified application

Species

Unspecified reactive species

Philipp Walch,Joel Selkrig,Leigh A Knodler,Mandy Rettel,Frank Stein,Keith Fernandez,Cristina Viéitez,Clément M Potel,Karoline Scholzen,Matthias Geyer,Klemens Rottner,Olivia Steele-Mortimer,Mikhail M Savitski,David W Holden,Athanasios Typas

Frontiers in cell and developmental biology 9:634708 PubMed33598464

2021

Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation.

Applications

Unspecified application

Species

Unspecified reactive species

Vanessa Dimchev,Ines Lahmann,Stefan A Koestler,Frieda Kage,Georgi Dimchev,Anika Steffen,Theresia E B Stradal,Franz Vauti,Hans-Henning Arnold,Klemens Rottner

Biology of the cell 113:107-117 PubMed33169848

2020

Caveolin-1 influences epithelial collective cell migration via FMNL2 formin.

Applications

Unspecified application

Species

Unspecified reactive species

Hiroko Katsuno-Kambe,Robert G Parton,Alpha S Yap,Jessica L Teo

Gene 710:186-192 PubMed31175924

2019

Inhibition of formin like 2 promotes the transition of ectopic endometrial stromal cells to epithelial cells in adenomyosis through a MET-like process.

Applications

Unspecified application

Species

Unspecified reactive species

You Li,Quan Zhang,Faying Liu,Ziyu Zhang,Yang Zou,Bicheng Yang,Yong Luo,Liqun Wang,Ouping Huang

The Journal of cell biology 217:3203-3218 PubMed29930204

2018

Cell adhesion is regulated by CDK1 during the cell cycle.

Applications

Unspecified application

Species

Unspecified reactive species

Matthew C Jones,Janet A Askari,Jonathan D Humphries,Martin J Humphries

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-FMNL2 antibody [2B4]

Western blot - Anti-FMNL2 antibody [2B4] (AB57963)

Key facts

Host species

Clonality

Clone number

Isotype

Light chain type

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Product details

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (14)

Product promise