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AB182918

Anti-Forssman antigen antibody [117C9]

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(1 Publication)

Rat Monoclonal Forssman antigen antibody. Suitable for IHC-Fr and reacts with Mouse samples. Cited in 1 publication. Immunogen corresponding to Tissue preparation containing Forssman antigen protein.

Key facts

Host species

Rat

Clonality

Monoclonal

Clone number

117C9

Isotype

IgM

Carrier free

No

Reacts with

Mouse

Applications

IHC-Fr

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

Specificity

ab182918 does not react exclusively with the Forssman antigen. In.a lipid extract fractionated by Folch partition of mouse mammary tumors the antibody also detects other glycolipid.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCFr" : {"fullname" : "Immunohistochemistry (Frozen sections)", "shortname":"IHC-Fr"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "IHCFr-species-checked": "guaranteed", "IHCFr-species-dilution-info": "", "IHCFr-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purity
IgM fraction
Storage buffer
Preservative: 0.09% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Forssman antigen also known as heterogenetic antigen functions as a glycolipid present on cell surfaces. This antigen typically consists of a carbohydrate moiety bound to a lipid contributing to its diverse role in biological systems. Forssman antigen is expressed in a variety of species including certain animals and some human cell types. Its molecular mass can vary due to its complex carbohydrate structure which influences its presence and interactions within tissues.
Biological function summary

Forssman antigen participates in intercellular recognition and immune responses. It exists within lipid rafts on cellular membranes and interacts with proteins involved in signal transduction. Although not a protein itself it plays a role when bound in lipid-protein complexes that can activate immune pathways. This antigen provides a form of molecular identification that cells use to communicate and interact with their environment.

Pathways

Forssman antigen interacts significantly with immune system processes and is critical for cellular communication. It appears in the complement pathway where it may interact with proteins such as C1 and C3 during immune responses. Sphingolipid metabolism pathways also involve Forssman antigen due to its linkage to lipid rafts and glycosphingolipids sharing connections with proteins like sphingomyelinase and glycosyltransferases.

Forssman antigen has connections to organ transplant rejection and autoimmune diseases. Its strong antigenic properties can trigger immune responses that jeopardize transplants interacting with proteins such as antibodies in the process. Additionally abnormal expression or recognition of Forssman antigen might contribute to conditions like systemic lupus erythematosus where it links to complement proteins in pathological immune activation.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Forssman antigen
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in cell and developmental biology 9:616711 PubMed33659248

2021

The miR-203a Regulatory Network Affects the Proliferation of Chronic Myeloid Leukemia K562 Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Jinhua He,Zeping Han,Ziyi An,Yumin Li,Xingyi Xie,Jiabin Zhou,Sihua He,Yubing Lv,Mengling He,Hong Qu,Gexiu Liu,Yuguang Li
View all publications
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