JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB236385

Anti-FOXN2 antibody [OTI5H8]

Be the first to review this product! Submit a review

|

(0 Publication)

Mouse Monoclonal FOXN2 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human FOXN2.

View Alternative Names

HTLF, FOXN2, Forkhead box protein N2, Human T-cell leukemia virus enhancer factor

1 Images
Western blot - Anti-FOXN2 antibody [OTI5H8] (AB236385)
  • WB

Supplier Data

Western blot - Anti-FOXN2 antibody [OTI5H8] (AB236385)

All lanes:

Western blot - Anti-FOXN2 antibody [OTI5H8] (ab236385) at 1/2000 dilution

Lane 1:

pCMV6-ENTRY control cDNA transfected HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate at 5 µg

Lane 2:

pCMV6-ENTRY FOXN2 cDNA transfected HEK-293T (Human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysate at 5 µg

Predicted band size: 47 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

OTI5H8

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human FOXN2.

P32314

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>" } } }
style
left-column
style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Purification notes
Purified from cell culture supernatant.
Storage buffer
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FOXN2 also known as Forkhead Box N2 represents a transcription factor that regulates gene expression. The protein has a mass of approximately 59 kDa and contains a DNA-binding domain known as the Forkhead domain. Researchers have observed FOXN2 expression across various tissues indicating its widespread biological function. Though FOXN2 does not have many popular aliases it plays significant role in cellular processes.
Biological function summary

FOXN2 influences development and cellular differentiation. It acts as a part of the regulation network for gene expression though it does not form a stable complex with other proteins. FOXN2 plays a role in cell cycle regulation where it controls specific target genes necessary for proliferation and development. This control extends to pathways that modulate cellular growth and differentiation.

Pathways

FOXN2 integrates into the broader network of transcriptional regulation in cellular development and differentiation. FOXN2 participates in the Wnt signaling pathway important for controlling cell fate determination. It also interacts with key proteins like β-catenin which links it to cellular growth processes. This connection allows FOXN2 to affect major signaling cascades contributing to normal development.

Abnormalities in FOXN2 function can lead to developmental disorders and cancers. Genetic mutations affecting FOXN2 have connections to certain types of cancer like breast cancer where it may influence tumor formation and progression. Research shows that FOXN2 interacts with proteins such as BRCA1 which further ties its dysregulation to cancer susceptibility. Understanding FOXN2 helps in developing potential therapeutic targets for these diseases.
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Binds to the purine-rich region in HTLV-I LTR.
See full target information FOXN2
style
left-column
style
left-column
style
right-column

Complementary Products

Primary Antibodies

AB92511

Anti-HLA-DR antibody [EPR3692]

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size|Advanced Validation

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HLA-DR antibody [EPR3692] (AB92511)

  • 4
  • 7
Primary Antibodies

AB75985

Anti-CD21 antibody [EP3093]

RabMAb|Recombinant

Western blot - Anti-CD21 antibody [EP3093] (AB75985)

  • 4
  • 6
Primary Antibodies

AB124673

Anti-Werner's syndrome helicase WRN antibody [EPR6392]

RabMAb|Recombinant|KO Validated

Western blot - Anti-Werner's syndrome helicase WRN antibody [EPR6392] (AB124673)

  • 4
  • 1
Primary Antibodies

AB16698

Anti-CD79a antibody [SP18]

RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD79a antibody [SP18] (AB16698)

  • 1
  • 1

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com