Skip to main content

Mouse Polyclonal FOXQ1 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human Forkhead box protein Q1 aa 100-250.

Be the first to review this product! Submit a review

Images

Western blot - Anti-FOXQ1 antibody (AB194564), expandable thumbnail
  • Western blot - Anti-FOXQ1 antibody (AB194564), expandable thumbnail

Key facts

Isotype

IgG

Host species

Mouse

Storage buffer

Constituents: 50% Glycerol (glycerin, glycerine)

Form

Liquid

Clonality

Polyclonal

Immunogen

  • Recombinant Fragment Protein within Human Forkhead box protein Q1 aa 100-250. The exact immunogen used to generate this antibody is proprietary information. Database link Q9C009

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WB
Human
Tested
Mouse
Predicted
Rat
Predicted

Tested
Tested

Species

Human

Dilution info

1/500 - 1/2500

Notes

-

Predicted
Predicted

Species

Mouse, Rat

Dilution info

-

Notes

-

Target data

Function

Plays a role in hair follicle differentiation.

Alternative names

Recommended products

Mouse Polyclonal FOXQ1 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human Forkhead box protein Q1 aa 100-250.

Key facts

Isotype

IgG

Form

Liquid

Clonality

Polyclonal

Immunogen
  • Recombinant Fragment Protein within Human Forkhead box protein Q1 aa 100-250. The exact immunogen used to generate this antibody is proprietary information. Database link Q9C009
Purity

Whole antiserum

Concentration
Loading...

Storage

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Supplementary info

This supplementary information is collated from multiple sources and compiled automatically.

Activity summary

FOXQ1 also known as Forkhead box Q1 is a transcription factor that regulates gene expression. Its molecular weight is approximately 44 kDa. FOXQ1 expression occurs in various tissues including the lungs intestines and certain parts of the brain. This protein belongs to the Forkhead box (FOX) family which plays key roles in numerous cellular processes. These transcription factors share a similar DNA-binding domain enabling binding to specific sequences and control of target gene expression.

Biological function summary

FOXQ1 influences cell proliferation differentiation and survival. It does not form part of a larger complex though it interacts with other proteins for its function. In particular FOXQ1 can modulate epithelial-mesenchymal transition (EMT) an essential process in development and cancer metastasis. Through its role in EMT FOXQ1 impacts cellular plasticity and tumor progression thereby influencing how cells respond to growth signals.

Pathways

Connections involving FOXQ1 include the TGF-beta signaling and Wnt pathways. These pathways are critical in controlling cellular growth and differentiation functions. Within these pathways FOXQ1 interacts with proteins such as SMAD and beta-catenin which further transmit signals to the nucleus altering gene expression patterns. Such interactions position FOXQ1 as a pivotal component in facilitating cellular responses to environmental stimuli.

Associated diseases and disorders

FOXQ1 has implications in cancer and fibrotic diseases. In cancers such as colorectal and breast cancer abnormal FOXQ1 expression can lead to more aggressive tumor phenotypes and poor prognosis. FOXQ1 associates with proteins like E-cadherin and Vimentin during cancer progression influencing tumor invasiveness and metastasis. In fibrosis FOXQ1 dysregulation affects tissue repair by modifying fibroblast activity and matrix deposition showcasing its role in pathological tissue remodeling.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

2 product images

  • Western blot - Anti-FOXQ1 antibody (ab194564), expandable thumbnail

    Western blot - Anti-FOXQ1 antibody (ab194564)

    All lanes: Western blot - Anti-FOXQ1 antibody (ab194564) at 1/500 dilution

    All lanes: HeLa S3 nuclear extract at 50 µg

    Developed using the ECL technique.

    Predicted band size: 41 kDa

  • Western blot - Anti-FOXQ1 antibody (ab194564), expandable thumbnail

    Western blot - Anti-FOXQ1 antibody (ab194564)

    Predicted MWt of immunogen: 38.21 kDa.

    All lanes: Western blot - Anti-FOXQ1 antibody (ab194564) at 1/1000 dilution

    All lanes: Recombinant Human FOXQ1 protein (immunogen) at 0.2 µg

    Developed using the ECL technique.

    Predicted band size: 28 kDa, 41 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com