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AB229666

Anti-FSD1 antibody

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(1 Publication)

Rabbit Polyclonal FSD1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human FSD1.

View Alternative Names

GLFND, MIR1, VLP27, FSD1, Fibronectin type III and SPRY domain-containing protein 1, MID1-related protein 1, Microtubule-associated protein GLFND

3 Images
Immunocytochemistry/ Immunofluorescence - Anti-FSD1 antibody (AB229666)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-FSD1 antibody (AB229666)

4% paraformaldehyde-fixed SK-N-SH (human neuroblastoma cell line) cells stained for FSD1 (green) using ab229666 at 1/500 dilution in ICC/IF.

Nuclear counterstain : Hoechst 33342 (blue).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FSD1 antibody (AB229666)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FSD1 antibody (AB229666)

Paraffin-embedded mouse brain tissue stained for FSD1 using ab229666 at 1/1200 dilution in immunohistochemical analysis.

Western blot - Anti-FSD1 antibody (AB229666)
  • WB

Supplier Data

Western blot - Anti-FSD1 antibody (AB229666)

10% SDS-PAGE gel.

All lanes:

Western blot - Anti-FSD1 antibody (ab229666) at 1/1000 dilution

Lane 1:

U87-MG (human glioblastoma-astrocytoma epithelial cell line) whole cell extract at 30 µg

Lane 2:

SK-N-SH (human neuroblastoma cell line) whole cell extract at 30 µg

Lane 3:

IMR32 (human neuroblast cell line) whole cell extract at 30 µg

Lane 4:

SK-N-AS (human neuroblastoma cell line) whole cell extract at 30 µg

Predicted band size: 56 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human FSD1. The exact immunogen used to generate this antibody is proprietary information.

Q9BTV5

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/1000", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/1200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

FSD1 also known as FSD1 calendar is a protein that plays a significant role in cellular processes. It weighs approximately 116 kDa. Researchers have observed its expression in various tissues with a prevalence in the brain and muscle tissues. FSD1 interacts with other cellular components to facilitate structural support and signaling pathways within these tissues.
Biological function summary

FSD1 contributes to maintaining cellular integrity and regulating signal transduction pathways. It is part of a larger complex which includes other structural proteins that assist in maintaining cell shape and stability. Scientists recognize its importance in modulating cellular responses to external stimuli influencing cellular behavior and adaptation.

Pathways

FSD1 operates in the cytoskeletal signaling pathway influencing cellular architecture and mechanical processes. It works in tandem with proteins like actin and tubulin which are important for maintaining cell shape and enabling movement. Additionally FSD1 is involved in the signaling pathways related to cell growth and repair further expanding its role in cellular health.

Researchers have linked FSD1 to cancer and neurological disorders. Changes in its expression or function can lead to structural and signaling imbalances contributing to these conditions. The protein interacts with other proteins like p53 and tau which are associated with cell cycle regulation and neurodegeneration respectively. Understanding these interactions helps us develop therapeutic strategies to target these diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

May be involved in microtubule organization and stabilization.
See full target information FSD1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Brain, behavior, and immunity 82:279-297 PubMed31505254

2019

TNF deficiency causes alterations in the spatial organization of neurogenic zones and alters the number of microglia and neurons in the cerebral cortex.

Applications

Unspecified application

Species

Unspecified reactive species

Minna Yli-Karjanmaa,Kathrine Solevad Larsen,Christina Dühring Fenger,Lotte Kellemann Kristensen,Nellie Anne Martin,Peter Toft Jensen,Alexandre Breton,Lubov Nathanson,Pernille Vinther Nielsen,Minna Christiansen Lund,Stephanie Lindeman Carlsen,Jan Bert Gramsbergen,Bente Finsen,Jane Stubbe,Lars Henrik Frich,Helen Stolp,Roberta Brambilla,Daniel Clive Anthony,Morten Meyer,Kate Lykke Lambertsen
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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