Rabbit Multiclonal FXR1 antibody. Suitable for ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human FXR1.
Images
![Immunocytochemistry/ Immunofluorescence - Anti-FXR1 antibody [RP23040192] (AB308117), expandable thumbnail](https://content.abcam.com/products/images/fxr1-antibody-rp23040192-ab308117--immunocytochemistry-immunofluorescence-img406932.jpg/_jcr_content/renditions/webp-475.webp "Immunocytochemistry/ Immunofluorescence - Anti-FXR1 antibody [RP23040192] (AB308117)")
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: 99.91% PBS- Form
Liquid
- Clonality
Multiclonal
Immunogen
- Recombinant Fragment Protein within Human FXR1. Database link P51114
Reactivity data
Select an application| ICC/IF | |
|---|---|
| Human | Tested |
ICC/IF
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 2 µg/mL | Notes - |
Target data
Function
RNA-binding protein required for embryonic and postnatal development of muscle tissue (PubMed:30770808). May regulate intracellular transport and local translation of certain mRNAs (By similarity).
Alternative names
Fragile X mental retardation syndrome-related protein 1, hFXR1p, FXR1
Recommended products
Rabbit Multiclonal FXR1 antibody. Suitable for ICC/IF and reacts with Human samples. Immunogen corresponding to Recombinant Fragment Protein within Human FXR1.
Alternative names
Fragile X mental retardation syndrome-related protein 1, hFXR1p, FXR1
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.4
Preservative: 0.09% Sodium azide
Constituents: 99.91% PBS- Form
Liquid
- Clonality
Multiclonal
- Immunogen
- Recombinant Fragment Protein within Human FXR1. Database link P51114
- Clone number
RP23040192
- Concentration
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
Notes
Recombinant multiclonals are a mixture of recombinant antibodies co-expressed from a library of heavy and light chains.
Recombinant multiclonal antibodies offer the sensitivity of polyclonal antibodies by recognising multiple epitopes, along with consistency of a recombinant antibody.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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1 product image
![Immunocytochemistry/ Immunofluorescence - Anti-FXR1 antibody [RP23040192] (ab308117), expandable thumbnail](https://content.abcam.com/products/images/fxr1-antibody-rp23040192-ab308117--immunocytochemistry-immunofluorescence-img406932.jpg "Immunocytochemistry/ Immunofluorescence - Anti-FXR1 antibody [RP23040192] (ab308117)")
Immunocytochemistry/ Immunofluorescence - Anti-FXR1 antibody [RP23040192] (ab308117)
For immunofluorescence analysis, A375 cells were fixed and permeabilized for detection of endogenous FXR1 using ab308117 at 2 µg/mL and labeled with a Goat anti-Rabbit IgG (H+L) Secondary Antibody, Alexa Fluor® 488 conjugate at 1/2000 dilution
Panel a) shows representative cells that were stained for detection and localization of FXR1 protein (green)
Panel b) is stained for nuclei (blue) using DAPI
Panel c) represents cytoskeletal F-actin staining using Alexa Fluor® 555 Rhodamine Phalloidin at 1/300 dilution
Panel d) is a composite image of Panels a, b and c clearly demonstrating FXR1 localization in stress granules (green) in cells treated with MG132 (25 uM, 5 hours)
Panel e) represents untreated cells with diffused cytoplasmic staining
Panel f) represents control cells with no primary antibody to assess background
The images were captured at 60X magnification.
Downloads
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