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AB131458

Anti-GAB1 (phospho Y627) antibody

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(1 Publication)

Rabbit Polyclonal GAB1 phospho Y627 antibody. Suitable for WB, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human GAB1 pY627.
2 Images
Immunocytochemistry/ Immunofluorescence - Anti-GAB1 (phospho Y627) antibody (AB131458)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-GAB1 (phospho Y627) antibody (AB131458)

Immunofluorescence staining of methanol fixed HeLa cells labelling GAB1 (phospho Y627) with ab131458 antibody at a dilution of 1/100.

Western blot - Anti-GAB1 (phospho Y627) antibody (AB131458)
  • WB

Unknown

Western blot - Anti-GAB1 (phospho Y627) antibody (AB131458)

All lanes:

Western blot - Anti-GAB1 (phospho Y627) antibody (ab131458) at 1/500 dilution

Lane 1:

HUVEC cell extracts untreated

Lane 2:

HUVEC cell extracts EGF treated

Predicted band size: 77 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB

applications

Immunogen

Synthetic Peptide within Human GAB1 pY627. The exact immunogen used to generate this antibody is proprietary information.

Q13480

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/200", "ICCIF-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Antibodies were purified by using epitope specific phospho peptide. Non-phospho specific antibodies were removed by chromatography using non-phospho peptide.
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Storage information
Stable for 12 months at -20°C
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Adapter protein that plays a role in intracellular signaling cascades triggered by activated receptor-type kinases. Plays a role in FGFR1 signaling. Probably involved in signaling by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Involved in the MET/HGF-signaling pathway (PubMed : 29408807).
See full target information GAB1 pY627

Alternative Names

GRB2-associated-binding protein 1, GRB2-associated binder 1, Growth factor receptor bound protein 2-associated protein 1, GAB1
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Publications (1)

Recent publications for all applications. Explore the full listand refine your search

Drug design, development and therapy 10:389-403 PubMed26855564

2016

Saussurea tridactyla Sch. Bip.-derived polysaccharides and flavones reduce oxidative damage in ultraviolet B-irradiated HaCaT cells via a p38MAPK-independent mechanism.

Applications

Unspecified application

Species

Unspecified reactive species

Yan Guo,Juan Sun,Juan Ye,Wenyu Ma,Hualing Yan,Gang Wang
View all publications
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Product promise

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