Rabbit Polyclonal GABA A Receptor alpha 3/GABRA3 antibody. Suitable for WB and reacts with Rat samples. Cited in 7 publications.
Images
Publications
Filter by
- International journal of molecular sciences 24:2023GABA Receptor β3 Subunit Mutation N328D Heterozygous Knock-in Mice Have Lennox-Gastaut Syndrome.Applications:Unspecified applicationReactive species:Unspecified reactive speciesGerald Ikemefuna Nwosu,Wangzhen Shen,Kirill Zavalin,Sarah Poliquin,Karishma Randhave,Carson Flamm,Marshall Biven,Katherine Langer,Jing-Qiong KangPubMed 37176165
- IBRO neuroscience reports 13:187-1972022Grape seed extract suppresses calcitonin gene-related peptide secretion and upregulates expression of GAD 65/67 and GABAB receptor in primary trigeminal ganglion cultures.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSophia R Antonopoulos,Paul L DurhamPubMed 36093283
- The Journal of clinical investigation 130:6555-65702020dmPFC-vlPAG projection neurons contribute to pain threshold maintenance and antianxiety behaviors.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJun-Bin Yin,Shao-Hua Liang,Fei Li,Wen-Jun Zhao,Yang Bai,Yi Sun,Zhen-Yu Wu,Tan Ding,Yan Sun,Hai-Xia Liu,Ya-Cheng Lu,Ting Zhang,Jing Huang,Tao Chen,Hui Li,Zhou-Feng Chen,Jing Cao,Rui Ren,Ya-Nan Peng,Juan Yang,Wei-Dong Zang,Xiang Li,Yu-Lin Dong,Yun-Qing LiPubMed 32841213
- Molecular neurobiology 57:4978-49882020Layers II/III of Prefrontal Cortex in Df(h22q11)/+ Mouse Model of the 22q11.2 Deletion Display Loss of Parvalbumin Interneurons and Modulation of Neuronal Morphology and Excitability.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAbdel-Rahman Al-Absi et. al.PubMed 32820460
- Molecular cancer 16:1672017miR-92b-3p acts as a tumor suppressor by targeting Gabra3 in pancreatic cancer.Applications:Unspecified applicationReactive species:Unspecified reactive speciesManmei Long et. al.PubMed 29078789
- Scientific reports 6:356592016Oxytocin modulates GABAR subunits to confer neuroprotection in stroke in vitro.
- Neuroscience 273:52-642014Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.Applications:Unspecified applicationReactive species:Unspecified reactive speciesR C Bates et. al.PubMed 24836856
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.5
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.238% HEPES, 0.01% BSA- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
Reactivity data
Select an application| WB | |
|---|---|
| Rat | Tested |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info 1/1000 | Notes - |
Associated Products
Select an associated product type
1 product for Alternative Product
Target data
Function
Alpha subunit of the heteropentameric ligand-gated chloride channel gated by gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain (PubMed:2153588). GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interface(s) (By similarity). When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient (By similarity). Chloride influx into the postsynaptic neuron following GABAAR opening decreases the neuron ability to generate a new action potential, thereby reducing nerve transmission (By similarity).
Alternative names
Gabra-3, Gabra3, Gamma-aminobutyric acid receptor subunit alpha-3, GABA(A) receptor subunit alpha-3, GABAAR subunit alpha-3
Recommended products
Rabbit Polyclonal GABA A Receptor alpha 3/GABRA3 antibody. Suitable for WB and reacts with Rat samples. Cited in 7 publications.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.5
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.238% HEPES, 0.01% BSA- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- The exact immunogen used to generate this antibody is proprietary information.
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-GABA A Receptor alpha 3/GABRA3 antibody (ab72446)
All lanes: Western blot - Anti-GABA A Receptor alpha 3/GABRA3 antibody (ab72446) at 1/1000 dilution
Lane 1: wild type rat brain lysates
Lane 2: GABA A Receptor alpha 3/GABRA3 knock out rat brain lysates
Predicted band size: 55 kDa
Observed band size: 55 kDa
Downloads
Product protocols
- Visit the general protocols
- Visit troubleshooting
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
For licensing inquiries, please contact partnerships@abcam.com