Rabbit Polyclonal GABA A Receptor beta 3/GABRB3 phospho S408 + S409 antibody. Suitable for WB and reacts with Rat samples. Immunogen corresponding to Synthetic Peptide within Rat Gabrb3 phospho S408 + S409.
Images
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.5
Constituents: HEPES, 50% Glycerol (glycerin, glycerine), 10% BSA, 0.87% Sodium chloride- Form
Liquid
- Clonality
Polyclonal
Immunogen
- Synthetic Peptide within Rat Gabrb3 phospho S408 + S409. The exact immunogen used to generate this antibody is proprietary information. Database link P63079
Reactivity data
Select an application| WB | |
|---|---|
| Human | Predicted |
| Mouse | Predicted |
| Rat | Tested |
| Chicken | Predicted |
| Cow | Predicted |
| Dog | Predicted |
| Primates | Predicted |
| Xenopus laevis | Predicted |
| Xenopus tropicalis | Predicted |
| Zebrafish | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Rat | Dilution info 1/1000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse, Chicken, Cow, Dog, Human, Xenopus laevis, Primates, Zebrafish, Xenopus tropicalis | Dilution info - | Notes - |
Target data
Function
Ligand-gated chloride channel which is a component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the brain (PubMed:2548852, PubMed:2540033). Plays an important role in the formation of functional inhibitory GABAergic synapses in addition to mediating synaptic inhibition as a GABA- gated ion channel (By similarity). The gamma2 subunit is necessary but not sufficient for a rapid formation of active synaptic contacts and the synaptogenic effect of this subunit is influenced by the type of alpha and beta subunits present in the receptor pentamer (By similarity). The alpha1/beta3/gamma2 receptor exhibits synatogenic activity whereas the alpha2/beta3/gamma2 receptor shows very little or no synaptogenic activity (By similarity). Functions also as histamine receptor and mediates cellular responses to histamine (By similarity). Plays an important role in somatosensation and in the production of antinociception (By similarity).
Alternative names
Gamma-aminobutyric acid receptor subunit beta-3, GABA(A) receptor subunit beta-3, GABRB3
Recommended products
Rabbit Polyclonal GABA A Receptor beta 3/GABRB3 phospho S408 + S409 antibody. Suitable for WB and reacts with Rat samples. Immunogen corresponding to Synthetic Peptide within Rat Gabrb3 phospho S408 + S409.
Alternative names
Gamma-aminobutyric acid receptor subunit beta-3, GABA(A) receptor subunit beta-3, GABRB3
Key facts
- Isotype
IgG
- Host species
Rabbit
- Storage buffer
pH: 7.5
Constituents: HEPES, 50% Glycerol (glycerin, glycerine), 10% BSA, 0.87% Sodium chloride- Form
Liquid
- Clonality
Polyclonal
- Immunogen
- Synthetic Peptide within Rat Gabrb3 phospho S408 + S409. The exact immunogen used to generate this antibody is proprietary information. Database link P63079
- Purification technique
Affinity purification Immunogen
- Concentration
- Purification notes
The antibody is prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho- and dephospho-peptide affinity columns.
Storage
- Shipped at conditions
Blue Ice
- Appropriate short-term storage duration
1-2 weeks
- Appropriate short-term storage conditions
+4°C
- Appropriate long-term storage conditions
-20°C
- Aliquoting information
Upon delivery aliquot
- Storage information
Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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1 product image
Western blot - Anti-GABA A Receptor beta 3/GABRB3 (phospho S408 + S409) antibody (ab254130)
All lanes: Western blot - Anti-GABA A Receptor beta 3/GABRB3 (phospho S408 + S409) antibody (ab254130) at 1/1000 dilution
Lane 1: Rat hippocampal lysate
Lane 2: Rat brain lysate
Predicted band size: 54 kDa
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