AB72448

Anti-GABA Transporter 1 / GAT 1 antibody

Name: Anti-GABA Transporter 1 / GAT 1 antibody (ab72448) | Abcam
Brand: Abcam Limited
SKU: AB72448
Rating: 4 (3 reviews)

(3 Reviews)

(6 Publications)

Rabbit Polyclonal GABA Transporter 1 / GAT 1 antibody. Suitable for WB and reacts with Rat samples. Cited in 6 publications.

View Alternative Names

Gabt1, Gat-1, Gat1, Slc6a1, Sodium- and chloride-dependent GABA transporter 1, GAT-1, Solute carrier family 6 member 1

1 Images

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Western blot - Anti-GABA Transporter 1 / GAT 1 antibody (AB72448)

All lanes:

Western blot - Anti-GABA Transporter 1 / GAT 1 antibody (ab72448) at 1/1000 dilution

All lanes:

rat hippocampal homogenate

Predicted band size: 67 kDa

Observed band size: 67 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Rat

Applications

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.5 Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.238% HEPES, 0.01% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Mediates transport of gamma-aminobutyric acid (GABA) together with sodium and chloride and is responsible for the reuptake of GABA from the synapse (PubMed : 18054861, PubMed : 1975955). The translocation of GABA, however, may also occur in the reverse direction leading to the release of GABA (PubMed : 18054861, PubMed : 21775701). The direction and magnitude of GABA transport is a consequence of the prevailing thermodynamic conditions, determined by membrane potential and the intracellular and extracellular concentrations of Na(+), Cl(-) and GABA (PubMed : 18054861, PubMed : 21775701). Also mediates sodium- and chloride-dependent transport of hypotaurine (By similarity).

See full target information Slc6a1

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Publications (6)

Recent publications for all applications. Explore the full list and refine your search

FEBS open bio 12:864-876 PubMed35147292

2022

Identification of sodium homeostasis genes in Camelus bactrianus by whole transcriptome sequencing.

Applications

Unspecified application

Species

Unspecified reactive species

Dong Zhang,Jing Pan,Chunxia Liu,Fanhua Meng,Yanru Zhang,Junwei Cao,Yu Cao,Huanmin Zhou

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35:e21869 PubMed34469026

2021

Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A.

Applications

Unspecified application

Species

Unspecified reactive species

Corinne S Wilson,Preeti Dohare,Shaina Orbeta,Julia W Nalwalk,Yunfei Huang,Russell J Ferland,Rajan Sah,Annalisa Scimemi,Alexander A Mongin

Developmental neuroscience 41:56-66 PubMed30904914

2019

Age-Dependent Electrocorticogram Dynamics and Epileptogenic Responsiveness in Rats Subjected to Prenatal Hypoxia.

Applications

Unspecified application

Species

Unspecified reactive species

Daria S Kalinina,Dmitrii S Vasilev,Anna B Volnova,Natalia N Nalivaeva,Igor A Zhuravin

Neurochemical research 43:1671-1682 PubMed29936569

2018

Transient Morphological Alterations in the Hippocampus After Pentylenetetrazole-Induced Seizures in Rats.

Applications

Unspecified application

Species

Unspecified reactive species

Dmitry S Vasilev,Natalia L Tumanova,Kira Kh Kim,Valeria V Lavrentyeva,Nera Y Lukomskaya,Igor A Zhuravin,Lev G Magazanik,Aleksey V Zaitsev

Neuropsychiatric disease and treatment 12:1731-7 PubMed27471387

2016

Involvement of upregulation of miR-210 in a rat epilepsy model.

Applications

Species

Unspecified reactive species

Licheng Chen,Hao Zheng,Shimeng Zhang

The European journal of neuroscience 42:3018-32 PubMed26390912

2015

Localization and expression of GABA transporters in the suprachiasmatic nucleus.

Applications

Unspecified application

Species

Unspecified reactive species

Michael Moldavan,Olga Cravetchi,Melissa Williams,Robert P Irwin,Sue A Aicher,Charles N Allen

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-GABA Transporter 1 / GAT 1 antibody

Western blot - Anti-GABA Transporter 1 / GAT 1 antibody (AB72448)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

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Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (6)

Product promise