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AB181783

Anti-GABA Transporter 3 / GAT 3 antibody

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(5 Publications)

Rabbit Polyclonal GABA Transporter 3 / GAT 3 antibody. Suitable for IHC-P and reacts with Human, Mouse, Rat samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Rat Slc6a11.

View Alternative Names

Gabt3, Gat-3, Gat-b, Slc6a11, Sodium- and chloride-dependent GABA transporter 3, GAT-3, Solute carrier family 6 member 11

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA Transporter 3 / GAT 3 antibody (AB181783)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GABA Transporter 3 / GAT 3 antibody (AB181783)

Immunohistochemical analysis of formalin fixed, paraffin embedded kidney tissue, labeling GABA Transporter 3 / GAT 3 with ab181783 at 1/50 dilution.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human, Mouse, Rat

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Rat Slc6a11. The exact immunogen used to generate this antibody is proprietary information.

P31647

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/50 - 1/500", "IHCP-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/50 - 1/500", "IHCP-species-notes": "<p></p>" }, "Rat": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/50 - 1/500", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Mediates sodium- and chloride-dependent transport of gamma-aminobutyric acid (GABA) (PubMed : 1400419, PubMed : 1497897). Can also mediate transport of beta-alanine and to a lower extent that of taurine and hypotaurine (By similarity).
See full target information Slc6a11
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Biomolecules & biomedicine 23:259-270 PubMed36226596

2023

Deletion of sphingosine kinase 2 attenuates cigarette smoke-mediated chronic obstructive pulmonary disease-like symptoms by reducing lung inflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Yanhui Chen,Yongrong Zhang,Cheng Rao,Jieyun Huang,Qiong Qing

Molecular psychiatry 27:855-864 PubMed34642457

2021

Astrocytes in the ventral pallidum extinguish heroin seeking through GAT-3 upregulation and morphological plasticity at D1-MSN terminals.

Applications

Unspecified application

Species

Unspecified reactive species

Anna Kruyer,Danielle Dixon,Ariana Angelis,Davide Amato,Peter W Kalivas

Journal of cell science 133: PubMed32938684

2020

Depression-like behaviors induced by defective PTPRT activity through dysregulated synaptic functions and neurogenesis.

Applications

Unspecified application

Species

Unspecified reactive species

So-Hee Lim,Sangyep Shin,Myoung-Hwan Kim,Eung Chang Kim,Da Yong Lee,Jeonghee Moon,Hye-Yeon Park,Young-Kyoung Ryu,Young-Mi Kang,Yu Jeong Kang,Tae Hwan Kim,Na-Yoon Lee,Nam-Soon Kim,Dae-Yeul Yu,Insop Shim,Yoichi Gondo,Masanobu Satake,Eunhee Kim,Kyoung-Shim Kim,Sun Seek Min,Jae-Ran Lee

Nature communications 11:4958 PubMed33009395

2020

GABA uptake transporters support dopamine release in dorsal striatum with maladaptive downregulation in a parkinsonism model.

Applications

Unspecified application

Species

Unspecified reactive species

Bradley M Roberts,Natalie M Doig,Katherine R Brimblecombe,Emanuel F Lopes,Ruth E Siddorn,Sarah Threlfell,Natalie Connor-Robson,Nora Bengoa-Vergniory,Nicholas Pasternack,Richard Wade-Martins,Peter J Magill,Stephanie J Cragg

Journal of neuroscience research 98:2349-2356 PubMed32856336

2020

Mechanisms underlying the enhancement of γ-aminobutyric acid responses in the external globus pallidus of R6/2 Huntington's disease model mice.

Applications

Unspecified application

Species

Unspecified reactive species

Joshua Barry,Theodore A Sarafian,Joseph B Watson,Carlos Cepeda,Michael S Levine
View all publications
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Product promise

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