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AB1398

Anti-GABARAP antibody

5

(1 Review)

|

(5 Publications)

Rabbit Polyclonal GABARAP antibody. Suitable for ELISA, WB and reacts with Mouse, Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human GABARAP aa 1-50.

View Alternative Names

FLC3B, HT004, GABARAP, Gamma-aminobutyric acid receptor-associated protein, GABA(A) receptor-associated protein, MM46

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

ELISA, WB

applications

Immunogen

Synthetic Peptide within Human GABARAP aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

O95166

Specificity

This antibody recognizes human GABARAP (14 kD).

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Mouse": { "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Ubiquitin-like modifier that plays a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton (PubMed : 9892355). Involved in autophagy : while LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed : 15169837, PubMed : 20562859, PubMed : 22948227). Through its interaction with the reticulophagy receptor TEX264, participates in the remodeling of subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover (PubMed : 31006538). Also required for the local activation of the CUL3(KBTBD6/7) E3 ubiquitin ligase complex, regulating ubiquitination and degradation of TIAM1, a guanyl-nucleotide exchange factor (GEF) that activates RAC1 and downstream signal transduction (PubMed : 25684205). Thereby, regulates different biological processes including the organization of the cytoskeleton, cell migration and proliferation (PubMed : 25684205). Involved in apoptosis (PubMed : 15977068).
See full target information GABARAP
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Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Insect science 30:365-374 PubMed36044542

2022

BmCaspase-8-like regulates autophagy by suppressing BmDREDD-mediated cleavage of BmATG6.

Applications

Unspecified application

Species

Unspecified reactive species

Chang Sun,Dongmei Wei,Yumeng Pan,Xiaoyi Xiao,Fei Wang

eLife 11: PubMed35170431

2022

Endurance exercise ameliorates phenotypes in models of spinocerebellar ataxias.

Applications

Unspecified application

Species

Unspecified reactive species

Alyson Sujkowski,Kristin Richardson,Matthew V Prifti,Robert J Wessells,Sokol V Todi

Molecular medicine reports 16:1509-1515 PubMed28586054

2017

Propofol reduces hypoxia‑induced autophagic cell death through downregulating HIF 1α in alveolar epithelial type II cells of rats.

Applications

Unspecified application

Species

Unspecified reactive species

Hui-Jie Ning,Hong-Bin Yuan,Hai-Tao Xu,Xing-Ying He

Molecular medicine reports 16:215-223 PubMed28534953

2017

Proteomic analysis of differentially expressed proteins in kidneys of brain dead rabbits.

Applications

WB

Species

Rabbit

Ling Li,Ning Li,Chongxiang He,Wei Huang,Xiaoli Fan,Zibiao Zhong,Yanfeng Wang,Qifa Ye

The Journal of comparative neurology 512:453-66 PubMed19034952

2008

Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome.

Applications

Unspecified application

Species

Mouse

Pavel V Belichenko,Alexander M Kleschevnikov,Eliezer Masliah,Chengbiao Wu,Ryoko Takimoto-Kimura,Ahmad Salehi,William C Mobley
View all publications
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Product promise

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