AB180768

Anti-GADD45A antibody

Name: Anti-GADD45A antibody (ab180768) | Abcam
Brand: Abcam Limited
SKU: AB180768
Price: 525 USD
Availability: InStock
Rating: 4 (1 reviews)

(1 Review)

(24 Publications)

Rabbit Polyclonal GADD45A antibody. Suitable for WB and reacts with Mouse samples. Cited in 24 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human GADD45A.

View Alternative Names

DDIT1, GADD45, GADD45A, Growth arrest and DNA damage-inducible protein GADD45 alpha, DNA damage-inducible transcript 1 protein, DDIT-1

1 Images

Supplier Data

Western blot - Anti-GADD45A antibody (AB180768)

Blocking buffer : 3% nonfat dry milk in TBST.

All lanes:

Western blot - Anti-GADD45A antibody (ab180768) at 1/1000 dilution

All lanes:

Extracts of mouse liver at 25 µg

Secondary

All lanes:

HRP Goat Anti-Rabbit IgG

Predicted band size: 18 kDa

true

Exposure time: 90s

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse

Applications

applications

Immunogen

Recombinant Full Length Protein corresponding to Human GADD45A.

P24522

style

left-column

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>" }, "Cat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chinese hamster": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.3 Preservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.

See full target information GADD45A

style

left-column

Publications (24)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in molecular neuroscience 18:1604670 PubMed40636523

2025

Critical gene network and signaling pathway analysis of the extracellular signal-regulated kinase (ERK) pathway in ischemic stroke.

Applications

Unspecified application

Species

Unspecified reactive species

Rui Mao,Lei Wang,Haitao Zhang,Jiaojiao Gong,Hua Liu

Discover. Oncology 14:26 PubMed36821012

2023

Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest.

Applications

Unspecified application

Species

Unspecified reactive species

Xia Yan,Dan Wang,Zhouyu Ning,Zhi-Qiang Meng

NPJ Regenerative medicine 7:53 PubMed36114225

2022

Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment.

Applications

Unspecified application

Species

Unspecified reactive species

Ye Sun,Jie Zhao,Qiang Wu,Yuxin Zhang,Yongqing You,Wenbo Jiang,Kerong Dai

JCI insight 6: PubMed34128833

2021

GADD45A is a protective modifier of neurogenic skeletal muscle atrophy.

Applications

Unspecified application

Species

Unspecified reactive species

Jeffrey T Ehmsen,Riki Kawaguchi,Damlanur Kaval,Anna E Johnson,Daniel Nachun,Giovanni Coppola,Ahmet Höke

Frontiers in oncology 11:616625 PubMed34094902

2021

Androgen Receptor, Although Not a Specific Marker For, Is a Novel Target to Suppress Glioma Stem Cells as a Therapeutic Strategy for Glioblastoma.

Applications

Unspecified application

Species

Unspecified reactive species

Nan Zhao,Fei Wang,Shaheen Ahmed,Kan Liu,Chi Zhang,Sahara J Cathcart,Dominick J DiMaio,Michael Punsoni,Bingjie Guan,Ping Zhou,Shuo Wang,Surinder K Batra,Tatiana Bronich,Tom K Hei,Chi Lin,Chi Zhang

Molecular and cellular biochemistry 476:3407-3421 PubMed33973132

2021

Silencing lncRNA-DGCR5 increased trophoblast cell migration, invasion and tube formation, and inhibited cell apoptosis via targeting miR-454-3p/GADD45A axis.

Applications

Unspecified application

Species

Unspecified reactive species

Yanlin Yang,Haixia Shang

Oncology reports 45: PubMed33846816

2021

Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45α/JNK/c‑Jun signalling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yao-Lei Zhang,Xu-Dong Wen,Xin Guo,Shang-Qing Huang,Ting-Ting Wang,Pei-Ting Zhou,Wei Li,Long-Fu Zhou,Yong-He Hu

Molecular therapy. Nucleic acids 23:872-886 PubMed33614236

2021

Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.

Applications

Unspecified application

Species

Unspecified reactive species

Chen Yang,Zezhong Mou,Zheyu Zhang,Siqi Wu,Quan Zhou,Yiling Chen,Jian Gong,Chenyang Xu,Yuxi Ou,Xinan Chen,Xiyu Dai,Haowen Jiang

Frontiers in oncology 10:1392 PubMed32974142

2020

LncRNA BC200 Promotes Esophageal Squamous Cell Cancer Migration and Invasion and Can Regulate ATF4 Expression.

Applications

Unspecified application

Species

Unspecified reactive species

Ruihua Zhao,Xinguang Cao,Shuiling Jin,Rui Li,Qian Zhong,Miao Jiang,Jinming Han,Changqing Guo,Hong Zong

Journal of cellular physiology 236:981-996 PubMed32617965

2020

Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes.

Applications

Unspecified application

Species

Unspecified reactive species

Cheng Peng,Sheng-Tao Hou,Chu-Xia Deng,Yandong Zhang

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-GADD45A antibody

Western blot - Anti-GADD45A antibody (AB180768)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (24)

Product promise