Rabbit Polyclonal GADD45A antibody. Suitable for WB and reacts with Mouse samples. Cited in 21 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human GADD45A.
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- Discover. Oncology 14:262023Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest.Applications:Unspecified applicationReactive species:Unspecified reactive speciesXia Yan,Dan Wang,Zhouyu Ning,Zhi-Qiang MengPubMed 36821012
- JCI insight 6:2021GADD45A is a protective modifier of neurogenic skeletal muscle atrophy.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJeffrey T Ehmsen,Riki Kawaguchi,Damlanur Kaval,Anna E Johnson,Daniel Nachun,Giovanni Coppola,Ahmet HökePubMed 34128833
- Frontiers in oncology 11:6166252021Androgen Receptor, Although Not a Specific Marker For, Is a Novel Target to Suppress Glioma Stem Cells as a Therapeutic Strategy for Glioblastoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesNan Zhao,Fei Wang,Shaheen Ahmed,Kan Liu,Chi Zhang,Sahara J Cathcart,Dominick J DiMaio,Michael Punsoni,Bingjie Guan,Ping Zhou,Shuo Wang,Surinder K Batra,Tatiana Bronich,Tom K Hei,Chi Lin,Chi ZhangPubMed 34094902
- Molecular and cellular biochemistry 476:3407-34212021Silencing lncRNA-DGCR5 increased trophoblast cell migration, invasion and tube formation, and inhibited cell apoptosis via targeting miR-454-3p/GADD45A axis.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYanlin Yang,Haixia ShangPubMed 33973132
- Oncology reports 45:2021Progesterone suppresses the progression of colonic carcinoma by increasing the activity of the GADD45α/JNK/c‑Jun signalling pathway.Applications:Unspecified applicationReactive species:Unspecified reactive speciesYao-Lei Zhang,Xu-Dong Wen,Xin Guo,Shang-Qing Huang,Ting-Ting Wang,Pei-Ting Zhou,Wei Li,Long-Fu Zhou,Yong-He HuPubMed 33846816
- Molecular therapy. Nucleic acids 23:872-8862021Circular RNA RBPMS inhibits bladder cancer progression via miR-330-3p/RAI2 regulation.Applications:Unspecified applicationReactive species:Unspecified reactive speciesChen Yang,Zezhong Mou,Zheyu Zhang,Siqi Wu,Quan Zhou,Yiling Chen,Jian Gong,Chenyang Xu,Yuxi Ou,Xinan Chen,Xiyu Dai,Haowen JiangPubMed 33614236
- Frontiers in oncology 10:13922020LncRNA BC200 Promotes Esophageal Squamous Cell Cancer Migration and Invasion and Can Regulate ATF4 Expression.Applications:Unspecified applicationReactive species:Unspecified reactive speciesRuihua Zhao et. al.PubMed 32974142
- Journal of cellular physiology 236:981-9962020Function of DHX33 in promoting Warburg effect via regulation of glycolytic genes.Applications:Unspecified applicationReactive species:Unspecified reactive speciesCheng Peng,Sheng-Tao Hou,Chu-Xia Deng,Yandong ZhangPubMed 32617965
- International journal of molecular sciences 21:2020Small Nucleolar RNAs Determine Resistance to Doxorubicin in Human Osteosarcoma.Applications:Unspecified applicationReactive species:Unspecified reactive speciesMartina Godel et. al.PubMed 32599901
- Molecular and cellular biology 40:2020DHX33 Recruits Gadd45a To Cause DNA Demethylation and Regulates a Subset of Gene Transcription.Applications:Unspecified applicationReactive species:Unspecified reactive speciesWeimin Feng et. al.PubMed 32312884
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49.91% PBS- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Recombinant Full Length Protein corresponding to Human GADD45A. Database link P24522
Reactivity data
Select an application| WB | |
|---|---|
| Mouse | Tested |
| Cat | Predicted |
| Chinese hamster | Predicted |
| Cow | Predicted |
WB
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/500.00000 - 1/2000.00000 | Notes - |
PredictedPredicted
| Species | Dilution info | Notes |
|---|---|---|
Species Cow, Cat, Chinese hamster | Dilution info - | Notes - |
Target data
Function
In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity (By similarity). Might affect PCNA interaction with some CDK (cell division protein kinase) complexes; stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
Alternative names
DDIT1, GADD45, GADD45A, Growth arrest and DNA damage-inducible protein GADD45 alpha, DNA damage-inducible transcript 1 protein, DDIT-1
Recommended products
Rabbit Polyclonal GADD45A antibody. Suitable for WB and reacts with Mouse samples. Cited in 21 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human GADD45A.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.3
Preservative: 0.09% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49.91% PBS- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Recombinant Full Length Protein corresponding to Human GADD45A. Database link P24522
- Purification technique
- Affinity purification Immunogen
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Aliquoting information
- Upon delivery aliquot
- Storage information
- Avoid freeze / thaw cycle
Notes
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
1 product image
Western blot - Anti-GADD45A antibody (ab180768)
Blocking buffer: 3% nonfat dry milk in TBST.
All lanes: Western blot - Anti-GADD45A antibody (ab180768) at 1/1000 dilution
All lanes: Extracts of mouse liver at 25 µg
SecondaryAll lanes: HRP Goat Anti-Rabbit IgG
Developed using the ECL technique.
Predicted band size: 18 kDa
Exposure time: 90s
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