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AB239501

Anti-Galectin 2 antibody [C6]

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(2 Publications)

Mouse Monoclonal Galectin 2 antibody. Suitable for WB, IHC-P and reacts with Mouse, Rat, Pig, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human Galectin-2.

View Alternative Names

Galectin-2, Gal-2, Beta-galactoside-binding lectin L-14-II, HL14, Lactose-binding lectin 2, S-Lac lectin 2, LGALS2

6 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Galectin 2 antibody [C6] (AB239501)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Galectin 2 antibody [C6] (AB239501)

Paraffin-embedded human esophagus tissue stained for Galectin 2 using ab239501 at 30 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Galectin 2 antibody [C6] (AB239501)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Galectin 2 antibody [C6] (AB239501)

Paraffin-embedded human kidney tissue stained for Galectin 2 using ab239501 at 30 μg/ml in immunohistochemical analysis. DAB staining.

Western blot - Anti-Galectin 2 antibody [C6] (AB239501)
  • WB

Supplier Data

Western blot - Anti-Galectin 2 antibody [C6] (AB239501)

All lanes:

Western blot - Anti-Galectin 2 antibody [C6] (ab239501) at 5 µg/mL

All lanes:

Recombinant human Galectin 2 protein

Predicted band size: 15 kDa

false

Western blot - Anti-Galectin 2 antibody [C6] (AB239501)
  • WB

Supplier Data

Western blot - Anti-Galectin 2 antibody [C6] (AB239501)

All lanes:

Western blot - Anti-Galectin 2 antibody [C6] (ab239501) at 3 µg/mL

All lanes:

Mouse stomach lysate

Secondary

All lanes:

HRP-Linked Goat anti-Mouse IgG at 0.2 µg/mL

Predicted band size: 15 kDa

false

Western blot - Anti-Galectin 2 antibody [C6] (AB239501)
  • WB

Supplier Data

Western blot - Anti-Galectin 2 antibody [C6] (AB239501)

All lanes:

Western blot - Anti-Galectin 2 antibody [C6] (ab239501) at 3 µg/mL

All lanes:

Pig stomach lysate

Secondary

All lanes:

HRP-Linked Goat anti-Mouse IgG at 0.2 µg/mL

Predicted band size: 15 kDa

false

Western blot - Anti-Galectin 2 antibody [C6] (AB239501)
  • WB

Supplier Data

Western blot - Anti-Galectin 2 antibody [C6] (AB239501)

All lanes:

Western blot - Anti-Galectin 2 antibody [C6] (ab239501) at 3 µg

All lanes:

Rat stomach lysate

Secondary

All lanes:

HRP-Linked Goat anti-Mouse IgG at 0.2 µg/mL

Predicted band size: 15 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

C6

Isotype

IgG2b

Light chain type

kappa

Carrier free

No

Reacts with

Mouse, Rat, Human, Pig

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human Galectin-2.

P05162

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-30 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Pig": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Purification notes
Purified from TCS.
Storage buffer
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Galectin 2 also known as LGALS2 is a member of the galectin family of beta-galactoside-binding proteins. It has a molecular mass of approximately 14 kDa. Galectin 2 is mainly expressed in the gastrointestinal tract and is found in tissues such as the small intestine colon and stomach. It functions mechanical as a carbohydrate-binding protein that interacts with cell surface glycoproteins and glycolipids influencing cell adhesion and signaling processes.
Biological function summary

Galectins like Galectin 2 play an important role in cell-cell interactions and cellular communication. Although not part of a larger complex Galectin 2 can bind to specific glycans modulating immune responses and inflammation. It can influence leukocyte migration and cytokine secretion contributing to the modulation of the immune system. Galectin 2 also impacts apoptosis and cell proliferation affecting tissue homeostasis and repair.

Pathways

Galectin 2 is involved in the regulation of immune response and inflammation pathways. It interacts with proteins such as integrins and glycoproteins affecting the signaling pathways that regulate immune cell activity. One example is the NF-kB signaling pathway where Galectin 2 can modulate the activation of this pathway influencing inflammation and immune responses. These interactions highlight its role in fine-tuning immune system functions during inflammation.

Galectin 2 has been implicated in inflammatory bowel disease (IBD) due to its expression in the gastrointestinal tract and role in inflammation. It is also associated with cardiovascular diseases as it influences inflammation and immune cell activity which are key in the development of atherosclerosis. Proteins like TNF-alpha known for their role in inflammation and immune responses have connections to Galectin 2 through these disease processes. Understanding Galectin 2's influence on these conditions provides insights into potential therapeutic strategies targeting inflammation and immune responses.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

This protein binds beta-galactoside. Its physiological function is not yet known.
See full target information Galectin-2
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Gland surgery 11:1518-1528 PubMed36221286

2022

LGALS2 suppresses the progression of papillary thyroid carcinoma by regulating the PI3K/AKT pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Debin Xu,Liangyun Guo,Shuyong Zhang,Qian Hou

Digestive diseases and sciences : PubMed32440745

2020

Development of Pancreatic Acinar Cell Metaplasia During Gastric Repair in a Rat Duodenal Contents Reflux Model.

Applications

Unspecified application

Species

Unspecified reactive species

Yasuhiro Wada,Ken-Ichi Mukaisho,Shunpei Kanai,Takahisa Nakayama,Masahide Fukuda,Kazuhiro Mizukami,Tadayoshi Okimoto,Masaaki Kodama,Hiroyuki Sugihara,Kazunari Murakami,Ryoji Kushima
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

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