Anti-GALR3 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

The interaction of GALR3 with galanin influences numerous physiological processes. GALR3 is not part of a known complex but functions independently to affect neural function. The receptor plays roles in modulating mood cognition and pain perception. It contributes to the regulation of neuroendocrine functions influencing hormone release and feeding behavior. GALR3's expression pattern and signaling capabilities suggest its involvement in fine-tuning nervous system responses.

Pathways

GALR3 is integrated into the neuropeptide signaling pathway and the G-protein signaling pathway. In the neuropeptide signaling pathway its interaction with galanin influences neurotransmitter release and synaptic plasticity. In the context of G-protein signaling GALR3 influences downstream effectors such as PLC and PI3K often working alongside related receptors like GALR1 and GALR2. These interactions reflect GALR3’s contribution to maintaining cellular homeostasis and response to external stimuli.