AB168370

Anti-GAS-7 antibody [EPR11129(B)]

Name: Anti-GAS-7 antibody [EPR11129(B)] (ab168370) | Abcam
Brand: Abcam Limited
SKU: AB168370
Price: 365 USD
Availability: InStock
Rating: 5 (1 reviews)

RabMAb
Recombinant
What is this?

(1 Review)

(2 Publications)

Rabbit Recombinant Monoclonal GAS-7 antibody. Suitable for IHC-P, WB, ICC/IF and reacts with Human, Mouse, Rat samples. Cited in 2 publications.

View Alternative Names

KIAA0394, GAS7, Growth arrest-specific protein 7, GAS-7

4 Images

Immunocytochemistry/ Immunofluorescence - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

Immunofluorescent analysis of U87-MG cells cells labeling GAS-7 with ab168370 at 1/50 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling GAS-7 with ab168370 at 1/100 dilution.

Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

Unknown

Western blot - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

All lanes:

Western blot - Anti-GAS-7 antibody [EPR11129(B)] (ab168370) at 1/1000 dilution

Lane 1:

fetal brain lysate at 10 µg

Lane 2:

Human cerebellum lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP at 1/2000 dilution

Predicted band size: 54 kDa

false

Unknown

Western blot - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

All lanes:

Western blot - Anti-GAS-7 antibody [EPR11129(B)] (ab168370) at 1/1000 dilution

Lane 1:

mouse brain tissue lysate at 10 µg

Lane 2:

rat brain tissue lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP conjugated at 1/2000 dilution

Predicted band size: 54 kDa

false

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR11129(B)

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

WB, IHC-P, ICC/IF

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/250", "IHCP-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/100", "ICCIF-species-notes": "" }, "Mouse": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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Product details

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form

Liquid

Purification technique

Affinity purification Protein A

Storage buffer

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Growth Arrest-Specific 7 often known as GAS7 is a protein with a molecular weight of approximately 48 kDa. GAS7 is known for its expression in neural tissues particularly in the brain where it plays an important role in cellular processes. This protein participates in the growth arrest of cells specifically in neurons indicating its importance in neurological functions.

Biological function summary

GAS7 contributes to the regulation of neuronal development and morphology. It is a part of various cellular complexes that guide the proper formation and differentiation of neurons. Studies show it helps in the development of the nerve cell cytoskeleton which is critical for maintaining neuronal architecture and function.

Pathways

The involvement of GAS7 includes those related to cytoskeletal organization and neuronal differentiation. Two significant pathways include the MAPK signaling pathway and the PI3K-Akt signaling pathway. GAS7 interacts with other proteins such as actin and filamin which are essential components in these pathways to regulate cell shape and motility.

GAS7 is linked to certain neurological conditions like neurodegenerative disorders and developmental issues. Abnormalities in GAS7 expression or function may have connections to disorders like Alzheimer's disease where cytoskeletal anomalies are common. Additionally its interaction with the protein tau which is implicated in Alzheimer's highlights its potential role in the manifestation of such diseases.

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

See full target information GAS7

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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

International journal of molecular sciences 24: PubMed37047359

2023

PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhen He,Teding Chang,Yu Chen,Hongjie Wang,Lei Dai,Hesong Zeng

mAbs 14:2020081 PubMed35030984

2022

Mitochondrial membrane potential-enriched CHO host: a novel and powerful tool for improving biomanufacturing capability.

Applications

Unspecified application

Species

Unspecified reactive species

Lina Chakrabarti,Raghothama Chaerkady,Junmin Wang,Shao Huan Samuel Weng,Chunlei Wang,Chen Qian,Lisa Cazares,Sonja Hess,Peter Amaya,Jie Zhu,Diane Hatton

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-GAS-7 antibody [EPR11129(B)]

Immunocytochemistry/ Immunofluorescence - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

Western blot - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

Western blot - Anti-GAS-7 antibody [EPR11129(B)] (AB168370)

Key facts

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

Complementary Products

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Product details

Properties and storage information

Form

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (2)

Product promise