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AB179814

Anti-GCET1 antibody [EPR12224]

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(1 Publication)

Rabbit Recombinant Monoclonal GCET1 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication.

View Alternative Names

GCET1, SERPINA11, UNQ692/PRO1337, SERPINA9, Serpin A9, Centerin, Germinal center B-cell-expressed transcript 1 protein

1 Images
Western blot - Anti-GCET1 antibody [EPR12224] (AB179814)
  • WB

Supplier Data

Western blot - Anti-GCET1 antibody [EPR12224] (AB179814)

All lanes:

Western blot - Anti-GCET1 antibody [EPR12224] (ab179814) at 1/1000 dilution

Lane 1:

MCF7 cell lysate at 10 µg

Lane 2:

Raji cell lysate at 10 µg

Lane 3:

Daudi cell lysate at 10 µg

Predicted band size: 47 kDa

false

  • Carrier free

    Anti-GCET1 antibody [EPR12224] - BSA and Azide free

Key facts

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR12224

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Product details

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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Properties and storage information

Form
Liquid
Purity
Tissue culture supernatant
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

GCET1 or germinal center B-cell expressed transcript 1 is a protein also known as CLL-1. It weighs approximately 43 kDa. This protein primarily appears in germinal center B-cells and shows up in some cases of diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma. It usually marks the cells involved in proliferation processes which are critical in some lymphomas’ pathogenesis and progression.
Biological function summary

GCET1 participates in the regulation of B-cell proliferation and survival although it is not itself a signaling molecule. It operates mainly within the immune system particularly affecting B-cells. This protein does not typically form part of a larger complex but may influence the activity of other proteins tied to B-cell activation and development aiding in the control of immune responses.

Pathways

GCET1 shows involvement with B-cell receptor signaling and associated signaling pathways. These pathways are central to lymphocyte development activation and differentiation. It interacts closely with essential signaling proteins like SYK and BLNK. Alterations in these pathways can contribute to improper B-cell functioning and linked immunological abnormalities.

GCET1 often relates to lymphoma particularly diffuse large B-cell lymphoma and follicular lymphoma. The protein GCET1 shows reciprocal connections with other molecules like BCL-6 in these cancers. Understanding GCET1 helps in identifying potential therapeutic targets and aids in diagnosing certain lymphoid malignancies underlining its value in clinical research related to these conditions.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Protease inhibitor that inhibits trypsin and trypsin-like serine proteases (in vitro). Inhibits plasmin and thrombin with lower efficiency (in vitro).
See full target information SERPINA9
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Cancer drug resistance (Alhambra, Calif.) 8:26 PubMed40521302

2025

PER2 expression and cellular localization play a critical role in tumor aggressiveness and drug resistance in an model of hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Mariarosaria Negri,Feliciana Amatrudo,Donatella Paola Provvisiero,Roberta Patalano,Giovanna Trinchese,Fabiano Cimmino,Cristina de Angelis,Chiara Simeoli,Renata Simona Auriemma,Maria Pina Mollica,Annamaria Colao,Rosario Pivonello,Claudia Pivonello
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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