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Mouse Monoclonal GDF11 antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human GDF11 aa 100-400.

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Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDF11 antibody [C4] (AB239515), expandable thumbnail
  • Western blot - Anti-GDF11 antibody [C4] (AB239515), expandable thumbnail
  • Western blot - Anti-GDF11 antibody [C4] (AB239515), expandable thumbnail

Publications

Key facts

Isotype
IgG2a
Host species
Mouse
Storage buffer

pH: 7.4
Preservative: 0.011% Proclin 300
Constituents: 55.77% Glycerol (glycerin, glycerine), 44.219% PBS

Form
Liquid
Clonality
Monoclonal

Immunogen

  • Recombinant Fragment Protein within Human GDF11 aa 100-400. The exact immunogen used to generate this antibody is proprietary information. Database link O95390

Reactivity data

Select an application
Product promiseTestedExpectedPredictedNot recommended
WBIHC-P
Human
Tested
Tested
Rat
Tested
Expected

Tested
Tested

Species
Rat
Dilution info
0.50000-5.00000 µg/mL
Notes

-

Species
Human
Dilution info
0.50000-5.00000 µg/mL
Notes

-

Tested
Tested

Species
Human
Dilution info
5.00000-30.00000 µg/mL
Notes

-

Expected
Expected

Species
Rat
Dilution info
Use at an assay dependent concentration.
Notes

-

Associated Products

Select an associated product type

2 products for Alternative Product

Target data

Function

Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues (By similarity). It is required for proper vertebral patterning and orofacial development (PubMed:31215115). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed:28257634).

Alternative names

BMP11, GDF11, Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11

Recommended products

Mouse Monoclonal GDF11 antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human GDF11 aa 100-400.

Key facts

Isotype
IgG2a
Form
Liquid
Clonality
Monoclonal
Immunogen
  • Recombinant Fragment Protein within Human GDF11 aa 100-400. The exact immunogen used to generate this antibody is proprietary information. Database link O95390
Clone number
C4
Purification technique
Affinity purification Protein A/G
Light chain type
kappa
Concentration
Loading...
Purification notes

Purified from TCS.

Storage

Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Notes

Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.

If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.

Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.

Product promise

We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.

In the unlikely event of one of our products not working as expected, you are covered by our product promise.

Full details and terms and conditions can be found here:
Terms & Conditions.

3 product images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDF11 antibody [C4] (ab239515), expandable thumbnail

    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDF11 antibody [C4] (ab239515)

    Paraffin-embedded human colorectal cancer tissue stained for GDF11 with ab239515 at 30 μg/ml in immunohistochemical analysis. DAB staining.

  • Western blot - Anti-GDF11 antibody [C4] (ab239515), expandable thumbnail

    Western blot - Anti-GDF11 antibody [C4] (ab239515)

    All lanes: Western blot - Anti-GDF11 antibody [C4] (ab239515) at 3 µg/mL

    All lanes: Rat spinal cord lysate

    Secondary

    All lanes: HRP-linked Goat Anti-Mouse IgG at 0.2 µg/mL

    Predicted band size: 45 kDa

  • Western blot - Anti-GDF11 antibody [C4] (ab239515), expandable thumbnail

    Western blot - Anti-GDF11 antibody [C4] (ab239515)

    All lanes: Western blot - Anti-GDF11 antibody [C4] (ab239515) at 5 µg/mL

    All lanes: Recombinant human GDF11 protein

    Predicted band size: 45 kDa

Downloads

Product protocols

For this product, it's our understanding that no specific protocols are required. You can:

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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