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AB239515

Anti-GDF11 antibody [C4]

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(2 Publications)

Mouse Monoclonal GDF11 antibody. Suitable for WB, IHC-P and reacts with Rat, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human GDF11 aa 100-400.

View Alternative Names

BMP11, GDF11, Growth/differentiation factor 11, GDF-11, Bone morphogenetic protein 11, BMP-11

3 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDF11 antibody [C4] (AB239515)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDF11 antibody [C4] (AB239515)

Paraffin-embedded human colorectal cancer tissue stained for GDF11 with ab239515 at 30 μg/ml in immunohistochemical analysis. DAB staining.

Western blot - Anti-GDF11 antibody [C4] (AB239515)
  • WB

Supplier Data

Western blot - Anti-GDF11 antibody [C4] (AB239515)

All lanes:

Western blot - Anti-GDF11 antibody [C4] (ab239515) at 5 µg/mL

All lanes:

Recombinant human GDF11 protein

Predicted band size: 45 kDa

false

Western blot - Anti-GDF11 antibody [C4] (AB239515)
  • WB

Supplier Data

Western blot - Anti-GDF11 antibody [C4] (AB239515)

All lanes:

Western blot - Anti-GDF11 antibody [C4] (ab239515) at 3 µg/mL

All lanes:

Rat spinal cord lysate

Secondary

All lanes:

HRP-linked Goat Anti-Mouse IgG at 0.2 µg/mL

Predicted band size: 45 kDa

false

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

C4

Isotype

IgG2a

Light chain type

kappa

Carrier free

No

Reacts with

Rat, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human GDF11 aa 100-400. The exact immunogen used to generate this antibody is proprietary information.

O95390

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-30 µg/mL", "IHCP-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Purification notes
Purified from TCS.
Storage buffer
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues (By similarity). It is required for proper vertebral patterning and orofacial development (PubMed : 31215115). Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3 (PubMed : 28257634).
See full target information GDF11
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in endocrinology 13:1029750 PubMed36568083

2022

Quercetin alleviates diastolic dysfunction and suppresses adverse pro-hypertrophic signaling in diabetic rats.

Applications

Unspecified application

Species

Unspecified reactive species

Linda Bartosova,Csaba Horvath,Peter Galis,Kristina Ferenczyova,Barbora Kalocayova,Adrian Szobi,Adriana Duris-Adameova,Monika Bartekova,Tomas Rajtik

Biomedical optics express 13:6659-6670 PubMed36589582

2022

All-fiber SPR microfluidic chip for GDF11 detection.

Applications

Unspecified application

Species

Unspecified reactive species

Yong Wei,Zhuo Ren,Ze Ran,Rui Wang,Chun-Biao Liu,Chen Shi,Chun-Lan Liu,Chen Wang,Yong-Hui Zhang
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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