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AB216417

Anti-GDNF Receptor alpha 2/GFRA2 antibody

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(1 Publication)

Rabbit Polyclonal GDNF Receptor alpha 2/GFRA2 antibody. Suitable for IHC-P and reacts with Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human GFRA2 aa 300-400 conjugated to Keyhole Limpet Haemocyanin.

View Alternative Names

GDNFRB, RETL2, TRNR2, GFRA2, GDNF family receptor alpha-2, GDNF receptor alpha-2, GDNFR-alpha-2, GFR-alpha-2, GDNF receptor beta, Neurturin receptor alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2, GDNFR-beta, NRTNR-alpha, NTNR-alpha

2 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDNF Receptor alpha 2/GFRA2 antibody (AB216417)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDNF Receptor alpha 2/GFRA2 antibody (AB216417)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue labeling GDNF Receptor alpha 2/GFRA2 with ab216417 at 1/200 dilution followed by Goat anti-rabbit IgG, PE conjugated, at 1/200 dilution for 40 minutes at 37°C

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDNF Receptor alpha 2/GFRA2 antibody (AB216417)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GDNF Receptor alpha 2/GFRA2 antibody (AB216417)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Rat brain labeling GDNF Receptor alpha 2/GFRA2 with ab216417 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat, Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human GFRA2 aa 300-400 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

O00451

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p>When using a fluorescent probe the recommended dilution is 1/50 – 1/200.</p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p>When using a fluorescent probe the recommended dilution is 1/50 – 1/200.</p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Receptor for neurturin (NRTN), a growth factor that supports the survival of sympathetic neurons (PubMed : 10829012, PubMed : 29414779, PubMed : 31535977, PubMed : 9182803). NRTN-binding leads to autophosphorylation and activation of the RET receptor (PubMed : 31535977). Also able to mediate GDNF signaling through the RET tyrosine kinase receptor (PubMed : 9182803).. Isoform 2. Participates in NRTN-induced 'Ser-727' phosphorylation of STAT3.
See full target information GFRA2
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 16:1397543 PubMed40206065

2025

The efficacy of ophiopogonanone B in treating the cough in mice infected with .

Applications

Unspecified application

Species

Unspecified reactive species

Nan-Nan Liu,Bai-Hui Guo,Lei Wang,Xiao-Xi Wang,Xin Wang,Yan-Li Meng,Gui-Xin Tang,Wei-Ming Wang
View all publications
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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