Rabbit Polyclonal GFAP antibody. Suitable for ICC, IHC-P and reacts with Mouse, Human samples. Cited in 59 publications. Immunogen corresponding to Native Full Length Protein corresponding to Cow GFAP.
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Publications
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- Frontiers in oncology 13:12536592023Single-cell RNA sequencing of neurofibromas reveals a tumor microenvironment favorable for neural regeneration and immune suppression in a neurofibromatosis type 1 porcine model.Applications:Unspecified applicationReactive species:Unspecified reactive speciesDalton T McLean,Jennifer J Meudt,Loren D Lopez Rivera,Dominic T Schomberg,Derek M Pavelec,Tyler T Duellman,Darya G Buehler,Patrick B Schwartz,Melissa Graham,Laura M Lee,Keri D Graff,Jamie L Reichert,Sandra S Bon-Durant,Charles M Konsitzke,Sean M Ronnekleiv-Kelly,Dhanansayan Shanmuganayagam,C Dustin RubinsteinPubMed 37817770
- Cell reports 42:1119882023Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neurons.Applications:Unspecified applicationReactive species:Unspecified reactive speciesOlli Pietiläinen,Aditi Trehan,Daniel Meyer,Jana Mitchell,Matthew Tegtmeyer,Vera Valakh,Hilena Gebre,Theresa Chen,Emilia Vartiainen,Samouil L Farhi,Kevin Eggan,Steven A McCarroll,Ralda NehmePubMed 36640364
- Frontiers in psychology 13:8890012022Regional Patterning of Adult Neurogenesis in the Homing Pigeon's Brain.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJulia Mehlhorn,Nelson Niski,Ke Liu,Svenja Caspers,Katrin Amunts,Christina HeroldPubMed 35898980
- ACS biomaterials science & engineering 8:2574-25882022Peripheral Nerve Decellularization for Extracellular Matrix Hydrogel Use: A Comparative Study.Applications:Unspecified applicationReactive species:Unspecified reactive speciesEmory Gregory,In Ha Baek,Nikolas Ala-Kokko,Reagan Dugan,Luis Pinzon-Herrera,Jorge Almodóvar,Young Hye SongPubMed 35649243
- Journal of neuroinflammation 19:682022Motoneuronal inflammasome activation triggers excessive neuroinflammation and impedes regeneration after sciatic nerve injury.Applications:Unspecified applicationReactive species:Unspecified reactive speciesKinga Molnár,Bernát Nógrádi,Rebeka Kristóf,Ádám Mészáros,Krisztián Pajer,László Siklós,Antal Nógrádi,Imola Wilhelm,István A KrizbaiPubMed 35305649
- PLoS biology 20:e30015302022Complementary encoding of spatial information in hippocampal astrocytes.Applications:Unspecified applicationReactive species:Unspecified reactive speciesSebastiano Curreli,Jacopo Bonato,Sara Romanzi,Stefano Panzeri,Tommaso FellinPubMed 35239646
- Fluids and barriers of the CNS 19:72022Met-RANTES preserves the blood-brain barrier through inhibiting CCR1/SRC/Rac1 pathway after intracerebral hemorrhage in mice.Applications:Unspecified applicationReactive species:Unspecified reactive speciesJun Yan,Weilin Xu,Cameron Lenahan,Lei Huang,Umut Ocak,Jing Wen,Gaigai Li,Wei He,Chensheng Le,John H Zhang,Ligen Mo,Jiping TangPubMed 35062973
- Journal of neuroinflammation 18:2732021Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer's disease.Applications:Unspecified applicationReactive species:Unspecified reactive speciesAvijit Banik,Radhika Amaradhi,Daniel Lee,Michael Sau,Wenyi Wang,Raymond Dingledine,Thota GaneshPubMed 34801055
- iScience 24:1032072021Synthetic amyloid-β oligomers drive early pathological progression of Alzheimer's disease in nonhuman primates.Applications:Unspecified applicationReactive species:Unspecified reactive speciesFeng Yue,Su Feng,Chunling Lu,Ting Zhang,Guoxian Tao,Jing Liu,Chunmei Yue,Naihe JingPubMed 34704001
- iScience 24:1029422021BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology.Applications:Unspecified applicationReactive species:Unspecified reactive speciesLiansheng Zhang,Yun Qian,Jie Li,Xuan Zhou,He Xu,Jie Yan,Jialing Xiang,Xiang Yuan,Beicheng Sun,Sangram S Sisodia,Yong-Hui Jiang,Xiaohua Cao,Naihe Jing,Anning LinPubMed 34430820
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.3 - 7.5
Preservative: 0.05% Sodium azide
Constituents: 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
Immunogen
- Native Full Length Protein corresponding to Cow GFAP. Database link Q28115
Reactivity data
Select an application| ICC | IHC-P | |
|---|---|---|
| Human | Expected | Tested |
| Mouse | Tested | Expected |
ICC
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info 1/100 | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
IHC-P
TestedTested
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info 1/50.00000 - 1/250.00000 | Notes - |
ExpectedExpected
| Species | Dilution info | Notes |
|---|---|---|
Species Mouse | Dilution info Use at an assay dependent concentration. | Notes - |
Associated Products
Select an associated product type
7 products for Alternative Product
Target data
Function
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Alternative names
Glial fibrillary acidic protein, GFAP
Recommended products
Rabbit Polyclonal GFAP antibody. Suitable for ICC, IHC-P and reacts with Mouse, Human samples. Cited in 59 publications. Immunogen corresponding to Native Full Length Protein corresponding to Cow GFAP.
Key facts
- Isotype
- IgG
- Host species
- Rabbit
- Storage buffer
pH: 7.3 - 7.5
Preservative: 0.05% Sodium azide
Constituents: 1% BSA- Form
- Liquid
- Clonality
- Polyclonal
- Immunogen
- Native Full Length Protein corresponding to Cow GFAP. Database link Q28115
- Purity
- IgG fraction
- Concentration
Storage
- Shipped at conditions
- Blue Ice
- Appropriate short-term storage duration
- 1-2 weeks
- Appropriate short-term storage conditions
- +4°C
- Appropriate long-term storage conditions
- -20°C
- Storage information
- Avoid freeze / thaw cycle
Notes
In the central nervous system, this antibody stains astrocytes and some groups of ependymal cells. However, in the peripheral nervous system, it stains Schwann cells, satellite cells and enteric glial cells.
Product promise
Tested
We have tested this species and application combination and it works. It is covered by our product promise.
Expected
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
Predicted
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
Not recommended
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
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3 product images
Photo courtesy of QBMCellScienceImmunocytochemistry - Anti-GFAP antibody - Astrocyte Marker (ab16997)
GFAP Immunocytochemistry staining using rabbit Anti-GFAP antibody
Mouse cortical primary astrocytes stained for GFAP using ab16997 at a dilution of 1/100 in ICC/IF.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFAP antibody - Astrocyte Marker (ab16997)
GFAP Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) staining using rabbit Anti-GFAP antibody
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human brain tissue, staining GFAP with ab16997.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFAP antibody - Astrocyte Marker (ab16997)
GFAP Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) staining using rabbit Anti-GFAP antibody
Formalin-fixed, paraffin-embedded section of human brain stained with antibodies to GFAP. Cytoplasmic staining of glia is shown in red.
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