AB176775

Anti-GFPT1 antibody

Name: Anti-GFPT1 antibody (ab176775) | Abcam
Brand: Abcam Limited
SKU: AB176775
Price: 520 USD
Availability: InStock

Be the first to review this product! Submit a review

(5 Publications)

Rabbit Polyclonal GFPT1 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human GFPT1 aa 500 to C-terminus.

View Alternative Names

GFAT, GFPT, GFPT1, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1, D-fructose-6-phosphate amidotransferase 1, Glutamine:fructose-6-phosphate amidotransferase 1, Hexosephosphate aminotransferase 1, GFAT 1, GFAT1

2 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFPT1 antibody (AB176775)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFPT1 antibody (AB176775)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human fetal testis tissue labeling GFPT1 with ab176775 at 1/100 dilution.

Supplier Data

Western blot - Anti-GFPT1 antibody (AB176775)

All lanes:

Western blot - Anti-GFPT1 antibody (ab176775) at 1/1000 dilution

Lane 1:

HeLa cell lysate

Lane 2:

Human kidney lysate

Predicted band size: 79 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human GFPT1 aa 500 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q06210

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/200 - 1/1000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

style

left-column

style

left-column

Properties and storage information

Form

Lyophilized

Reconstitution

reconstitute with water at 200µL

Purification technique

Affinity purification Immunogen

Storage buffer

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1 (By similarity). Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling (PubMed : 26887390).

See full target information GFPT1

style

left-column

Publications (5)

Recent publications for all applications. Explore the full list and refine your search

Science advances 11:eadq0334 PubMed40249802

2025

Targeting PGM3 abolishes SREBP-1 activation-hexosamine synthesis feedback regulation to effectively suppress brain tumor growth.

Applications

Unspecified application

Species

Unspecified reactive species

Huali Su,Yaogang Zhong,Liqing He,Feng Geng,Xinmin Yin,Yongjun Kou,Cheng-Yao Chiang,Xiaokui Mo,Yunzhou Fan,Yanwei Liu,Qiang Wang,Shino Magaki,Timothy F Cloughesy,Etienne Lefai,William H Yong,Arnab Chakravarti,Xiang Zhang,Deliang Guo

Virology 531:183-191 PubMed30927711

2019

Human metapneumovirus infection of airway epithelial cells is associated with changes in core metabolic pathways.

Applications

Unspecified application

Species

Unspecified reactive species

Yanhua Zhao,Harendra Singh Chahar,Narayana Komaravelli,Anar Dossumekova,Antonella Casola

Oncotarget 8:19205-19217 PubMed28186970

2017

High expression of GFAT1 predicts unfavorable prognosis in patients with hepatocellular carcinoma.

Applications

IHC

Species

Human

Lili Li,Miaomiao Shao,Peike Peng,Caiting Yang,Shushu Song,Fangfang Duan,Dongwei Jia,Mingming Zhang,Junjie Zhao,Ran Zhao,Weicheng Wu,Lan Wang,Can Li,Hao Wu,Jie Zhang,Xin Wu,Yuanyuan Ruan,Jianxin Gu

Scientific reports 6:39044 PubMed27996048

2016

High expression of GFAT1 predicts poor prognosis in patients with pancreatic cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Caiting Yang,Peike Peng,Lili Li,Miaomiao Shao,Junjie Zhao,Lan Wang,Fangfang Duan,Shushu Song,Hao Wu,Jie Zhang,Ran Zhao,Dongwei Jia,Mingming Zhang,Weicheng Wu,Can Li,Yefei Rong,Lei Zhang,Yuanyuan Ruan,Jianxin Gu

Oncotarget 7:38427-39 PubMed27509259

2016

Loss of GFAT1 promotes epithelial-to-mesenchymal transition and predicts unfavorable prognosis in gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Fangfang Duan,Dongwei Jia,Junjie Zhao,Weicheng Wu,Lingqiang Min,Shushu Song,Hao Wu,Lan Wang,Hongshan Wang,Yuanyuan Ruan,Jianxin Gu

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-GFPT1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFPT1 antibody (AB176775)

Western blot - Anti-GFPT1 antibody (AB176775)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Reactivity data

Properties and storage information

Form

Reconstitution

Purification technique

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (5)

Alternative Products

Primary Antibodies

Primary Antibodies

Complementary Products

Assay Kits

Primary Antibodies

Secondary Antibodies

Primary Antibodies

Primary Antibodies

Product promise