Rabbit Polyclonal GIMAP6 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human GIMAP6 aa 1-250.
View Alternative Names
IAN2, IAN6, GIMAP6, GTPase IMAP family member 6, Immunity-associated nucleotide 2 protein, Immunity-associated nucleotide 6 protein, IAN-2, hIAN2, IAN-6, hIAN6
- WB
Unknown
Western blot - Anti-GIMAP6 antibody (AB126067)
12% SDS PAGE
All lanes:
Western blot - Anti-GIMAP6 antibody (ab126067) at 1/1000 dilution
All lanes:
MCF7 whole cell lysate at 30 µg
Predicted band size: 33 kDa
false
Reactivity data
Properties and storage information
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Storage buffer
Shipped at conditions
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
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Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The functions involving GTPase such as GIMAP6 regulate immune cell survival and homeostasis. It participates in critical cellular processes like apoptosis and autophagy often interacting with other members of the GIMAP family. GIMAP6 involvement suggests its integration in protein complexes that maintain cellular balance and response to stressors. Due to these activities GIMAP6 helps to modulate cell fate decisions in lymphocytes and perhaps other immune cells.
Pathways
Knowledge about GIMAP6 connects it to the regulation of autophagy and apoptosis pathways. It possibly interacts with molecules like Beclin-1 which plays a central role in the autophagy pathway. These interactions imply a connection to the PI3K/Akt signaling pathway where GIMAP proteins can influence survival signals and cellular responses. Therefore GIMAP6 has the potential to intersect with pathways involving other GTPase family proteins highlighting its influence within immune signaling networks.
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Target data
Publications (1)
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Molecular medicine reports 14:4119-4123 PubMed27667392
2016
Applications
IHC-P
Species
Human
Product promise
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