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AB236974

Anti-GLT8D1 antibody

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(2 Publications)

Rabbit Polyclonal GLT8D1 antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Mouse, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human GLT8D1 aa 1-350.

View Alternative Names

GALA4A, AD-017, MSTP137, UNQ572/PRO1134, GLT8D1, Glycosyltransferase 8 domain-containing protein 1

5 Images
Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)

HepG2 (Human liver hepatocellular carcinoma cell line) cells stained for GLT8D1 (green) using ab236974 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)

Paraffin-embedded human liver tissue stained for GLT8D1 using ab236974 at 1/100 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-GLT8D1 antibody (AB236974)

PC-3 (Human prostate adenocarcinoma cell line) cells stained for GLT8D1 (green) using ab236974 at 1/100 dilution in ICC/IF, followed by Alexa Fluor 488® conjugated Goat Anti-Rabbit IgG (H+L).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GLT8D1 antibody (AB236974)

Paraffin-embedded human kidney tissue stained for GLT8D1 using ab236974 at 1/100 dilution in immunohistochemical analysis.

Western blot - Anti-GLT8D1 antibody (AB236974)
  • WB

Supplier Data

Western blot - Anti-GLT8D1 antibody (AB236974)

All lanes:

Western blot - Anti-GLT8D1 antibody (ab236974) at 1/500 dilution

All lanes:

Mouse liver lysate

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/10000 dilution

Predicted band size: 42 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

ICC/IF, WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human GLT8D1 aa 1-350. The exact immunogen used to generate this antibody is proprietary information.

Q68CQ7

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein G
Purification notes
Purity >95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

GLT8D1 also known as Glycosyltransferase 8 domain containing 1 is an enzyme that participates in glycosylation catalyzing the addition of sugars to proteins or lipids. The protein has a mass of approximately 46 kDa. GLT8D1 expression occurs widely including in tissues like the liver and brain. This expression pattern suggests GLT8D1 plays several important roles in various physiological processes.
Biological function summary

GLT8D1 contributes to the modification and stability of proteins. It is not currently recognized as part of a larger complex but interacts within cellular mechanisms to maintain protein function. The enzyme affects cell signaling and communication by modifying surface proteins impacting processes such as development and immune response.

Pathways

GLT8D1 is involved in the protein glycosylation pathway contributing to the modification of glycoproteins. This pathway plays a role in proteostasis affecting quality control of proteins. GLT8D1 might work alongside other glycosyltransferases such as MGATs which also participate in protein modification although specific direct interactions might not be well-characterized.

GLT8D1 mutations or altered activity have been associated with certain neurodegenerative conditions such as spinocerebellar ataxia. In these diseases disruptions in glycosylation processes might impact overall neuronal function and stability. GLT8D1 might also engage indirectly with proteins like ataxin which participate in related pathways affecting neuronal health and disease progression.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information GLT8D1
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in immunology 13:907636 PubMed35967419

2022

Spindle pole body component 25 and platelet-derived growth factor mediate crosstalk between tumor-associated macrophages and prostate cancer cells.

Applications

Unspecified application

Species

Unspecified reactive species

Feilun Cui,Zhipeng Xu,Jianpeng Hu,Yumei Lv

Cell death and differentiation 29:1834-1849 PubMed35301431

2022

Hypoxia-induced GLT8D1 promotes glioma stem cell maintenance by inhibiting CD133 degradation through N-linked glycosylation.

Applications

Unspecified application

Species

Unspecified reactive species

Kun Liu,Liping Jiang,Yulin Shi,Baiyang Liu,Yaomei He,Qiushuo Shen,Xiulin Jiang,Zhi Nie,Jun Pu,Cuiping Yang,Yongbin Chen
View all publications
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