Anti-Glycogenin 2 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

As a self-glucosylating enzyme glycogenin 2 plays an important role in glycogen particle formation. It exists as a homodimer a reflection of its ability to self-prime and extend glucose polymers. Through this activity it helps maintain the balance of energy supply in cells a function critical in tissues with high energy demands. Despite its catalytic role it interacts with other enzymes such as glycogen synthase to carry out its biological activities effectively.

Pathways

The enzymatic activity of glycogenin 2 is central to glycogen biosynthesis. It acts upstream of the glycogen synthesis pathway providing the necessary primer for glycogen synthase to extend the glucose chain. This pathway is vital for glucose storage regulation in organisms. Glycogenin 2 works alongside proteins like UDP-glucose pyrophosphorylase which supplies the active glucose moiety for glycogen chain elongation.