JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB324963

Anti-Glycoprotein N Crimean-Congo hemorrhagic fever virus antibody [JE12]

Be the first to review this product! Submit a review

|

(0 Publication)

Mouse Recombinant Monoclonal Glycoprotein N antibody. Suitable for I-ELISA and reacts with Recombinant fragment - Crimean-Congo hemorrhagic fever virus strain IbAr10200 samples.

View Alternative Names

Envelopment polyprotein, M polyprotein, GP

1 Images
Indirect ELISA - Anti-Glycoprotein N Crimean-Congo hemorrhagic fever virus antibody [JE12] (AB324963)
  • I-ELISA

Supplier Data

Indirect ELISA - Anti-Glycoprotein N Crimean-Congo hemorrhagic fever virus antibody [JE12] (AB324963)

Indirect ELISA analysis of ab324963 at 2000-0 ng/ml. The Secondary antibody used was Alkaline Phosphatase-conjugated AffiniPure Goat Anti-Mouse IgG (H+L) at 1 : 1000 dilution dilution.

Antigen : Glycoprotein N Crimean-Congo hemorrhagic fever virus, Nucleoprotein Crimean-Congo hemorrhagic fever virus.

Antigen concentration : 1000 ng/ml

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

JE12

Isotype

IgG1

Carrier free

No

Reacts with

Crimean-Congo hemorrhagic fever virus strain IbAr10200

Applications

I-ELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IELISA" : {"fullname" : "Indirect ELISA", "shortname":"I-ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Crimean-Congo hemorrhagic fever virus strain IbAr10200": { "IELISA-species-checked": "predicted", "IELISA-species-dilution-info": "", "IELISA-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" }, "Recombinant fragment - Crimean-Congo hemorrhagic fever virus strain IbAr10200": { "IELISA-species-checked": "testedAndGuaranteed", "IELISA-species-dilution-info": "125 ng/mL", "IELISA-species-notes": "<p></p>", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
style
left-column
style
left-column

Product details

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Want a custom formulation?
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com

style
left-column

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

Target data

Glycoprotein N. Plays a role in virion attachment to host receptor (PubMed : 38182887). This attachment induces virion internalization predominantly through clathrin-dependent endocytosis (PubMed : 19088291) Glycoprotein N probably locks the Gn-Gc complex in a prefusion state (PubMed : 34793197).. Glycoprotein C. Binds to host cell surface receptor LDLR and mediates fusion between viral and cellular membranes (PubMed : 38182887). Attachment to receptor induces virion internalization predominantly through clathrin-dependent endocytosis (PubMed : 19088291). Class II fusion protein that promotes fusion of viral membrane with host endosomal membrane after endocytosis of the virion (PubMed : 34793197, PubMed : 35234630). Exposure of the glycoprotein spikes to potassium is necessary for the conformational change leading to fusion (By similarity).
See full target information GP
style
left-column
style
left-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions
style
left-column
style
right-column
style
bg-slate-100

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com