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AB150485

Anti-GPCR GPR115 antibody - C-terminal

2

(5 Reviews)

|

(1 Publication)

Rabbit Polyclonal GPCR GPR115 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human ADGRF4.

View Alternative Names

GPR115, PGR18, ADGRF4, Adhesion G protein-coupled receptor F4, G-protein coupled receptor 115, G-protein coupled receptor PGR18

1 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR115 antibody - C-terminal (AB150485)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GPCR GPR115 antibody - C-terminal (AB150485)

Immunohistochemical analysis of paraffin embedded Human breast, epithelium tissue labelling GPCR GPR115 with ab150485 antibody at a concentration of 10 µg/ml.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human ADGRF4. The exact immunogen used to generate this antibody is proprietary information.

Q8IZF3

Specificity

BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except GPR113 (69%).

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "4-10 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Common marmoset": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Dog": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Elephant": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Gorilla": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Horse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Monkey": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rabbit": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.1% Sodium azide Constituents: PBS
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The GPCR GPR115 also known as adhesion G protein-coupled receptor F4 or ADGRF4 is a member of the adhesion GPCR family. This protein is characterized by a large extracellular region that contains various domains which may facilitate cell adhesion processes. It has an approximate mass of 145 kDa. GPR115 is expressed mainly in human tissues like the lung and skin.
Biological function summary

The GPCR GPR115 influences cellular processes such as signal transduction and cell matrix interactions. It plays important roles in mediating cellular responses to external stimuli. GPR115 does not function as part of a protein complex but might interact with other membrane proteins to exert its functions. It shows evolving roles being explored in various physiological contexts.

Pathways

GPCR GPR115 is involved in pathways associated with signal transduction. Specifically it plays a role in G protein-coupled receptor signaling. It potentially interacts with similar proteins like GPCR GPR116 which is another member of the same family facilitating coordination within the signaling cascades. These pathways are key in transmitting signals from the extracellular environment to the inside of the cell affecting cellular behavior.

GPCR GPR115 may have links to respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). Altered expression of this receptor in lung tissue can influence disease progression. This GPCR shares pathways with proteins like the GPCR GPR116 which may also play roles in these conditions providing potential targets for therapeutic approaches.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Orphan receptor.
See full target information ADGRF4
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Biology 12: PubMed37998017

2023

Acetylcholine, Another Factor in Breast Cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Juan P Muñoz,Gloria M Calaf
View all publications
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Product promise

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