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BiochemicalsProteins and Peptides
Proteins and peptidesAnti-Ly6g antibody [1A8] - mouse IgG2c (Chimeric)
Low endotoxin, Azide free.
Our first-to-market chimera with mouse IgG2c backbone, this functional antibody specifically depletes neutrophils in vivo for up to 72h.
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Rabbit Polyclonal GPCR GPR87 antibody. C-terminal. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human GPR87.
IgG
Rabbit
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 99% PBS
Liquid
Polyclonal
IHC-P | |
---|---|
Human | Tested |
Mouse | Predicted |
Rat | Predicted |
Cow | Predicted |
Dog | Predicted |
Gorilla | Predicted |
Hamster | Predicted |
Horse | Predicted |
Monkey | Predicted |
Pig | Predicted |
Rabbit | Predicted |
Species | Dilution info | Notes |
---|---|---|
Species Human | Dilution info 6.00000-14.00000 µg/mL | Notes Perform heat-mediated antigen retrieval before commencing with IHC staining protocol. |
Species | Dilution info | Notes |
---|---|---|
Species Mouse, Rat, Rabbit, Horse, Hamster, Cow, Dog, Pig, Gorilla, Monkey | Dilution info - | Notes - |
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.
G-protein coupled receptor 87, G-protein coupled receptor 95, GPR87, GPR95, FKSG78
Rabbit Polyclonal GPCR GPR87 antibody. C-terminal. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human GPR87.
G-protein coupled receptor 87, G-protein coupled receptor 95, GPR87, GPR95, FKSG78
IgG
Rabbit
pH: 7.4
Preservative: 0.1% Sodium azide
Constituents: 99% PBS
Liquid
Polyclonal
Synthetic Peptide within Human GPR87. The exact immunogen used to generate this antibody is proprietary information.Database link Q9BY21
Affinity purification Immunogen
BLAST analysis of the peptide immunogen showed no homology with other Human proteins, except YSK4 (63%).
Blue Ice
1-2 weeks
+4°C
-20°C
Upon delivery aliquot
Avoid freeze / thaw cycle
Abcam is leading the way to address reproducibility in scientific research with our highly validated recombinant monoclonal and recombinant multiclonal antibodies. Search & select one of Abcam's thousands of recombinant alternatives to eliminate batch-variability and unnecessary animal use.
If you do not find a host species to meet your needs, our catalogue and custom Chimeric range provides scientists the specificity of Abcam's RabMAbs in the species backbone of your choice. Remember to also review our range of edited cell lines, proteins and biochemicals relevant to your target that may help you further your research goals.
Abcam antibodies are extensively validated in a wide range of species and applications, so please check the reagent specifications meet your scientific needs before purchasing. If you have any questions or bespoke requirements, simply visit the Contact Us page to send us an inquiry or contact our Support Team ahead of purchase.
In mediating cellular communication GPR87 plays a role in autocrine signaling mechanisms. It is not typically part of a larger complex but works closely with ligands and other signaling molecules to exert its effects. Studies indicate that GPR87 activation could promote cell proliferation and survival particularly in cancerous tissues suggesting a role in oncogenic pathways and cellular homeostasis.
GPCR GPR87 also known as G protein-coupled receptor 87 is a transmembrane receptor involved in various signaling processes. It has a molecular weight of approximately 42 kDa. GPR87 is expressed in various tissues with higher levels in certain cancers such as lung and bladder cancers. This receptor belongs to the large GPCR family which functions in transmitting signals from outside the cell to the inside leading to various cellular responses.
Multiple studies indicate that GPR87 participates in the p53 and Wnt signaling pathways. It might modulate the expression of target proteins such as p53 which is an important player in cell cycle regulation and apoptosis. GPR87 interacts with other proteins within these pathways potentially contributing to the regulatory loops that control cell fate and proliferation.
Researchers link GPR87 with lung and bladder cancer due to its overexpression in these tissues. It correlates with tumor aggression and poor prognosis indicating its role in cancer progression. The p53 protein a well-known tumor suppressor interacts with GPR87 adding complexity to the regulatory networks involved in these cancers. Understanding GPR87's contributions to these diseases may offer insights for developing targeted therapies.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
We are dedicated to supporting your work with high quality reagents and we are here for you every step of the way should you need us.
In the unlikely event of one of our products not working as expected, you are covered by our product promise.
Full details and terms and conditions can be found here:
Terms & Conditions.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human prostate epithelium labeling GPCR GPR87 with ab188901 at 14 μg/ml.
Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.
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