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AB128234

Anti-Gr28b antibody

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Rabbit Polyclonal GR28B antibody. Suitable for WB, ELISA and reacts with Drosophila melanogaster samples. Immunogen corresponding to Synthetic Peptide within Drosophila melanogaster Gr28b.

View Alternative Names

CG13788, Gr28b, Putative gustatory receptor 28b

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Drosophila melanogaster

Applications

WB, ELISA

applications

Immunogen

Synthetic Peptide within Drosophila melanogaster Gr28b. The exact immunogen used to generate this antibody is proprietary information.

Q9VM08

Specificity

ab128234 reacts with Drosophila melanogaster Gr28b isoform B.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Drosophila melanogaster": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
Constituents: 2% Sucrose, 1.21% Tris, 0.75% Glycine
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Gr28b also known as Gustatory receptor 28b functions mechanically as a gustatory receptor in Drosophila melanogaster. This receptor weighs approximately 37 kDa and is primarily expressed in sensory neurons particularly in the labellum and tarsi. Gr28b's role involves detecting specific chemical stimuli contributing to the fly's ability to respond to various taste cues.
Biological function summary

This receptor plays a role in taste perception and chemosensory processes within the gustatory system of Drosophila. Gr28b is not a part of any larger protein complex but operates as a single unit within sensory neurons. It detects specific chemical components allowing the fly to discern between different food sources and potentially harmful substances.

Pathways

Gr28b contributes significantly to the gustation pathway within Drosophila which is critical for feeding behavior. This receptor works alongside other gustatory receptors in the fly such as Gr5a to mediate the detection of diverse tastants. Together these receptors integrate signals that modulate feeding decisions and other gustatory-driven behaviors.

Gr28b's functions in taste perception and feeding behaviors link to research on obesity and metabolic disorders in Drosophila models. While not directly associated with human diseases it serves as a model for understanding similar mechanisms in humans. Other proteins connected to these studies include insulin and its pathway components which influence metabolic processes influenced by taste perception.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Probable gustatory receptor which mediates acceptance or avoidance behavior, depending on its substrates (By similarity). Atypical expression suggests also nongustatory roles in the nervous system and tissues involved in proprioception, hygroreception, and other sensory modalities. It is also possible that it has chemosensory roles in the detection of internal ligands.
See full target information Gr28b
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