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AB229858

Anti-GSTM3 antibody

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(2 Publications)

Rabbit Polyclonal GSTM3 antibody. Suitable for WB and reacts with Mouse, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human GSTM3.

View Alternative Names

GST5, GSTM3, Glutathione S-transferase Mu 3, GST class-mu 3, GSTM3-3, hGSTM3-3

1 Images
Western blot - Anti-GSTM3 antibody (AB229858)
  • WB

Supplier Data

Western blot - Anti-GSTM3 antibody (AB229858)

All lanes:

Western blot - Anti-GSTM3 antibody (ab229858) at 1/1000 dilution

All lanes:

Mouse kidney tissue lysate

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/50000 dilution

Predicted band size: 27 kDa

Observed band size: 27 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human GSTM3.

P21266

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Reactivity data

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
Purity >95%.
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

GSTM3 also known as Glutathione S-transferase Mu 3 is a protein that plays a role in detoxification processes. This enzyme belongs to the GST superfamily which assists in conjugating glutathione to hydrophobic and electrophilic compounds. GSTM3 has a molecular weight of approximately 26 kDa. It is expressed in various tissues including the brain liver and testis indicating its involvement in diverse physiological functions.
Biological function summary

GSTM3 facilitates the neutralization of reactive oxygen species protecting cells from oxidative damage. This protein interacts with intracellular substrates engaging in phase II metabolic reactions. While GSTM3 does not form larger multimeric complexes it partners with glutathione to stabilize and detoxify harmful compounds. This role highlights GSTM3’s importance within cellular defense mechanisms.

Pathways

GSTM3 participates in the xenobiotic metabolism and the glutathione pathway. These pathways involve the biotransformation of toxic substances where GSTM3 works in tandem with related proteins like CYP450 enzymes. GSTM3's activity in the glutathione pathway interconnects with the regulation of oxidative stress highlighting its part in cellular resilience against environmental challenges.

GSTM3 has connections to neurological disorders and certain cancers. Its involvement in detoxification processes links it to the neurodegenerative condition Parkinson's disease where oxidative stress plays a critical role. In certain cancers variations in GSTM3 expression levels influence tumor development and aggressiveness. GSTM3's interaction with proteins involved in these conditions such as GSTP1 offers potential insights into therapeutic strategies.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May govern uptake and detoxification of both endogenous compounds and xenobiotics at the testis and brain blood barriers.
See full target information GSTM3
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Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Communications biology 8:1040 PubMed40640354

2025

Fortilin deficiency induces anti-atherosclerotic phenotypes in macrophages and protects hypercholesterolemic mice against atherosclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Nattaporn Wanachottrakul,Decha Pinkaew,Sandipan Mukherjee,Preedakorn Chunhacha,Mari Nakashima,Asa A Brockman,Uttariya Pal,Hasseri B Halim,Yuhong Wei,Lena Tanaka,Hanna Huynh,Kota Ramana,Shiyou Chen,Rebecca A Ihrie,Ken Fujise

Journal of food biochemistry 46:e14500 PubMed36515171

2022

Laminarin ameliorates alcohol-induced liver damage and its molecular mechanism in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Tianyi Guo,Lingfeng Zhu,Yaping Zhou,Shuai Han,Yunyun Cao,Zuomin Hu,Yi Luo,Liyuan Bao,Xiuxiu Wu,Dandan Qin,Qinlu Lin,Feijun Luo
View all publications
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