AB231792

Anti-GSTT2 antibody

Be the first to review this product! Submit a review

(1 Publication)

Rabbit Polyclonal GSTT2 antibody. Suitable for WB, IHC-P and reacts with Mouse, Rat, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human GSTT2B aa 1 to C-terminus.

View Alternative Names

GSTT2, GSTT2B, Glutathione S-transferase theta-2B, Glutathione S-transferase theta-2, GST class-theta-2

6 Images

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSTT2 antibody (AB231792)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSTT2 antibody (AB231792)

Formalin-fixed, paraffin-embedded human liver tissue stained for GSTT2 using ab231792 at 20 μg/mL in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSTT2 antibody (AB231792)

Formalin-fixed, paraffin-embedded human kidney tissue stained for GSTT2 using ab231792 at 20 μg/mL in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSTT2 antibody (AB231792)

Formalin-fixed, paraffin-embedded human glioma tissue stained for GSTT2 using ab231792 at 10 μg/mL in immunohistochemical analysis. DAB staining.

Supplier Data

Western blot - Anti-GSTT2 antibody (AB231792)

All lanes:

Western blot - Anti-GSTT2 antibody (ab231792) at 2 µg/mL

All lanes:

Mouse lung lysate

Predicted band size: 28 kDa

true

Supplier Data

Western blot - Anti-GSTT2 antibody (AB231792)

All lanes:

Western blot - Anti-GSTT2 antibody (ab231792) at 1 µg/mL

All lanes:

Rat kidney lysate.

Predicted band size: 28 kDa

true

Supplier Data

Western blot - Anti-GSTT2 antibody (AB231792)

All lanes:

Western blot - Anti-GSTT2 antibody (ab231792) at 2 µg/mL

All lanes:

Recombinant human GSTT2 protein

Predicted band size: 28 kDa

true

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Mouse, Rat, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human GSTT2B aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P0CG30

style

left-column

style

left-column

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

style

left-column

style

left-column

Properties and storage information

Form

Liquid

Purification technique

Affinity purification Immunogen

Purification notes

Antigen-specific affinity chromatography followed by Protein A affinity chromatography.

Storage buffer

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

Shipped at conditions

Blue Ice

Appropriate short-term storage duration

1-2 weeks

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

style

left-column

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

GSTT2 also known as Glutathione S-transferase Theta-2 belongs to the GST superfamily of enzymes. This protein has an approximate molecular mass of 27 kDa. GSTT2 is involved in the conjugation of reduced glutathione to various electrophilic compounds facilitating the detoxification process. It is expressed in several tissues with notable presence in the liver kidney and testis. GSTT2 plays a role in processing many xenobiotic substances enhancing cell resistance to oxidative stress.

Biological function summary

GSTT2 facilitates the detoxification process by catalyzing reactions that neutralize harmful compounds. It catalyzes the conjugation of glutathione to form less reactive electrophilic or hydrophobic substances. GSTT2 does not function as part of a larger complex within cells but has an important role in maintaining the redox balance. The enzyme contributes to cellular defense mechanisms ensuring proper cellular functions in stressful environments.

Pathways

The activity of GSTT2 has connections to the glutathione metabolism and drug metabolism pathways. These pathways are important for neutralizing endogenous and exogenous toxins. In the glutathione metabolism pathway GSTT2 works in conjunction with other GST enzymes like GSTP1 and GSTA1 to manage oxidative stress. The protein indirectly supports cellular detoxification processes influencing how effectively a cell can endure and adapt to toxic insults.

GSTT2's role in detoxification links it to conditions such as cancer and liver diseases. Altered GSTT2 expression has associations with the development of hepatocellular carcinoma. The protein interacts with related GST family members like GSTM1 and GSTP1 which play roles in modulating cancer susceptibility. Due to its role in processing carcinogens and protecting tissues from oxidative damage GSTT2 presents as a noteworthy protein in understanding disease mechanisms and potential therapeutic targets.

style

left-column

style

left-column

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

Target data

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (PubMed : 1417752). Has a sulfatase activity (PubMed : 1417752).

See full target information GSTT2B

style

left-column

Publications (1)

Recent publications for all applications. Explore the full list and refine your search

NPJ Regenerative medicine 10:19 PubMed40253438

2025

Allogeneic RPE cell suspension manufactured at scale demonstrating preclinical safety and efficacy led to IND approval.

Applications

Unspecified application

Species

Unspecified reactive species

Lalitha Soundararajan,Harshini Surendran,Niharika Patlolla,Rajani Battu,Jonathan Stoddard,Sebastian Arrizabalaga,Zengping Liu,Gopal Lingam,Xinyi Su,Renee C Ryals,Rajarshi Pal

View all publications

style

left-column

style

left-column

style

right-column

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-GSTT2 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSTT2 antibody (AB231792)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSTT2 antibody (AB231792)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GSTT2 antibody (AB231792)

Western blot - Anti-GSTT2 antibody (AB231792)

Western blot - Anti-GSTT2 antibody (AB231792)

Western blot - Anti-GSTT2 antibody (AB231792)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Alternative Products

Primary Antibodies

Complementary Products

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity data

Properties and storage information

Form

Purification technique

Purification notes

Storage buffer

Shipped at conditions

Appropriate short-term storage duration

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Supplementary information

Biological function summary

Pathways

Product protocols

Target data

Publications (1)

Product promise