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AB231568

Anti-H-FABP antibody

5

(1 Review)

|

(3 Publications)

Rabbit Polyclonal H-FABP antibody. Suitable for WB, IHC-P and reacts with Mouse, Pig samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Pig FABP3.

View Alternative Names

Fabph1, Fabp3, Fatty acid-binding protein 3, Heart-type fatty acid-binding protein, Mammary-derived growth inhibitor, H-FABP, MDGI

7 Images
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-H-FABP antibody (AB231568)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-H-FABP antibody (AB231568)

Paraffin-embedded pig heart tissue stained for H-FABP using ab231568 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-H-FABP antibody (AB231568)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-H-FABP antibody (AB231568)

Paraffin-embedded pig spleen tissue stained for H-FABP using ab231568 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Western blot - Anti-H-FABP antibody (AB231568)
  • WB

Supplier Data

Western blot - Anti-H-FABP antibody (AB231568)

All lanes:

Western blot - Anti-H-FABP antibody (ab231568) at 2 µg/mL

All lanes:

Recombinant pig H-FABP protein

Predicted band size: 15 kDa

false

Western blot - Anti-H-FABP antibody (AB231568)
  • WB

Supplier Data

Western blot - Anti-H-FABP antibody (AB231568)

All lanes:

Western blot - Anti-H-FABP antibody (ab231568) at 2 µg/mL

All lanes:

Mouse heart lysate

Predicted band size: 15 kDa

false

Western blot - Anti-H-FABP antibody (AB231568)
  • WB

Supplier Data

Western blot - Anti-H-FABP antibody (AB231568)

All lanes:

Western blot - Anti-H-FABP antibody (ab231568) at 3 µg/mL

Lane 1:

Pig heart lysate

Lane 2:

Pig skeletal muscle lysate

Lane 3:

Mouse heart lysate

Secondary

All lanes:

HRP-Linked Guinea pig anti-Rabbit at 1/1000 dilution

Predicted band size: 15 kDa

false

Western blot - Anti-H-FABP antibody (AB231568)
  • WB

Supplier Data

Western blot - Anti-H-FABP antibody (AB231568)

All lanes:

Western blot - Anti-H-FABP antibody (ab231568) at 2 µg

All lanes:

Pig heart lysate

Predicted band size: 15 kDa

false

Western blot - Anti-H-FABP antibody (AB231568)
  • WB

Supplier Data

Western blot - Anti-H-FABP antibody (AB231568)

All lanes:

Western blot - Anti-H-FABP antibody (ab231568) at 2 µg/mL

All lanes:

Pig skeletal muscle lysate

Predicted band size: 15 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Pig

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Pig FABP3.

O02772

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Pig": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab231568 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage buffer
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

H-FABP also known as heart-type fatty acid binding protein is a small protein with a molecular mass of approximately 14.5 kDa. This protein is primarily found in the cytoplasm of cardiac muscle cells but it also can be detected in skeletal muscles and other tissues at lower concentrations. H-FABP binds long-chain fatty acids and is important for the intracellular transport and metabolism of these molecules. The protein is often used as a biomarker for cardiac injury due to its rapid release into the bloodstream following muscle damage.
Biological function summary

Fatty acid binding largely defines H-FABP's role facilitating the transport of fatty acids within cells which is key for energy production. It is not part of a larger protein complex but plays into broader lipid metabolism processes. The efficiency of H-FABP in fatty acid binding and transport helps maintain cellular energy homeostasis especially in tissues with high fatty acid metabolism like the heart.

Pathways

H-FABP integrates into the fatty acid metabolic pathways and the beta-oxidation pathway. It is associated with the transport and utilization of fatty acids linking it to the peroxisome proliferator-activated receptor (PPAR) signaling pathway an important regulator of lipid metabolism. Proteins such as CD36 and PPARα interact with H-FABP within these pathways influencing lipid storage and energy balance.

Disruptions in H-FABP levels or function correlate with cardiovascular diseases including myocardial infarction. Elevated blood levels of H-FABP provide early markers of cardiac cell injury. Additionally alterations can also relate to metabolic disorders like obesity where lipid metabolism gets impaired. In these contexts proteins such as troponin and creatine kinase may also serve as biomarkers elucidating the relationship between H-FABP and myocardial stress or damage.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

FABPs are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.
See full target information Fabp3
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Publications (3)

Recent publications for all applications. Explore the full list and refine your search

Journal of Cancer 16:2388-2400 PubMed40302797

2025

MiR-371b-5p reduces osteosarcoma cell migration and proliferation to induce apoptosis by targeting FUT4.

Applications

Unspecified application

Species

Unspecified reactive species

Qiang Xue,Ruicong Ma,YueYuan Chen,Xiaodi Yan,Jiajia Liu,Jianhua Xue,Yang Yang,Xianchen Liu

Frontiers in nutrition 10:1098715 PubMed36969813

2023

Sodium acetate regulates milk fat synthesis through the activation of GPR41/GPR43 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yingao Qi,Tenghui Zheng,Xinghong Liu,Siwang Yang,Qihui Li,Jiayuan Shao,Xiangfang Zeng,Wutai Guan,Shihai Zhang

Cell communication and signaling : CCS 20:25 PubMed35248054

2022

Energy deprivation-induced AMPK activation inhibits milk synthesis by targeting PrlR and PGC-1α.

Applications

Unspecified application

Species

Unspecified reactive species

Zhihui Wu,Qihui Li,Siwang Yang,Tenghui Zheng,Jiayuan Shao,Wutai Guan,Fang Chen,Shihai Zhang
View all publications
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