Anti-HCC1 antibody

Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Biological function summary

HCC1 influences cell division and growth regulation as part of a larger protein complex. It interacts with components such as cyclins and CDKs to ensure proper progression through the cell cycle. The protein modulates the stability and degradation of specific cyclins therefore contributing to orderly cell cycle transitions. These activities position HCC1 as an important player in maintaining chromosomal stability further integrating it with mitotic checkpoint machinery.

Pathways

The interaction of HCC1 integrates into pivotal pathways like the cell cycle regulatory pathway and the Wnt signaling pathway. The cell cycle pathway involves interactions with CDKs and cyclins affecting checkpoints and transitions. In the Wnt signaling context HCC1 interacts with proteins like β-catenin helping to harmonize cellular proliferation signals and the cell cycle's momentum. These interactions indicate the adaptability of HCC1 within complex pathway networks essential for cellular proliferation and signaling.