Anti-hCG antibody
5
(1 Review)
|
(9 Publications)
Rabbit Polyclonal GLHA antibody. Suitable for WB, IHC-Fr, IHC-P and reacts with Human samples. Cited in 9 publications.
View Alternative Names
Glycoprotein hormones alpha chain, Anterior pituitary glycoprotein hormones common subunit alpha, Choriogonadotropin alpha chain, Chorionic gonadotrophin subunit alpha, Follicle-stimulating hormone alpha chain, Follitropin alpha chain, Luteinizing hormone alpha chain, Lutropin alpha chain, Thyroid-stimulating hormone alpha chain, Thyrotropin alpha chain, CG-alpha, FSH-alpha, LSH-alpha, TSH-alpha, CGA
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-hCG antibody (AB9376)
ab9376 staining hCG in formalin-fixed, paraffin-embedded Human placenta by Immunohistochemistry.
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-hCG antibody (AB9376)
Human normal placenta. Staining is localised extracellular and in the cytoplasm. Left panel : with primary antibody at 2 ug/ml. Right panel : isotype control. Sections were stained using an automated system DAKO Autostainer Plus , at room temperature : sections were rehydrated and antigen retrieved with the Dako 3 in 1 AR buffers citrate EDTA pH 9.0 in a DAKO PT Link. Slides were peroxidase blocked in 3% H2O2 in methanol for 10 mins. They were then blocked with Dako Protein block for 10 minutes (containing casein 0.25% in PBS) then incubated with primary antibody for 20 min and detected with Dako envision flex amplification kit for rabbit for 30 minutes. Colorimetric detection was completed with Diaminobenzidine for 5 minutes. Slides were counterstained with Haematoxylin and coverslipped under DePeX. Please note that for manual staining we recommend to optimize the primary antibody concentration and incubation time (overnight incubation), and amplification may be required.
Reactivity data
Properties and storage information
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Shipped at conditions
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Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
HCG regulates several functions related to reproduction. It supports the corpus luteum in ovaries to secrete progesterone during early pregnancy contributing to the uterine lining's maintenance. Moreover hCG can interact with the luteinizing hormone/chorionic gonadotropin receptor (LHCGR) indicating its involvement in broader reproductive functions. Not as well known hCG may exist in various forms such as hCG intact influencing certain biological pathways differently.
Pathways
Scientists study hCG's role in reproductive signaling and gonadotropin pathways. It interacts closely with luteinizing hormone (LH) with substantial overlap in their pathway functions impacting reproductive health and fertility cycles. hCG's activation of specific receptors like LHCGR plays a role in these pathways connecting it to various fertility-related responses in the human body.
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Target data
Publications (9)
Recent publications for all applications. Explore the full list and refine your search
Physiological reports 13:e70383 PubMed40415650
2025
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Nature biotechnology : PubMed37932420
2023
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The Journal of biological chemistry 296:100386 PubMed33556374
2021
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Physiological reports 9:e14671 PubMed33403800
2021
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Laboratory investigation; a journal of technical m 97:1188-1200 PubMed28287635
2017
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Fertility and sterility 105:1620-1627.e3 PubMed26920257
2016
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Unspecified reactive species
Biochemical and biophysical research communication 434:460-5 PubMed23583402
2013
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Unspecified reactive species
PloS one 7:e52567 PubMed23285091
2012
Applications
IHC-Fr
Species
Human
Endocrinology 150:2882-8 PubMed19196802
2009
Applications
ICC/IF
Species
Human
Product promise
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