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AB231584

Anti-Hemoglobin antibody

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(1 Publication)

Rabbit Polyclonal Hemoglobin subunit alpha antibody. Suitable for WB and reacts with Recombinant full length protein - Monkey, Human, Dog samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Rhesus monkey Hemoglobin subunit alpha.

View Alternative Names

HBA2, HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain

4 Images
Western blot - Anti-Hemoglobin antibody (AB231584)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231584)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231584) at 2 µg/mL

All lanes:

Human blood cell lysate

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231584)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231584)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231584) at 2 µg/mL

All lanes:

Recombinant monkey hemoglobin protein.

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231584)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231584)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231584) at 2 µg/mL

All lanes:

Canine serum

Predicted band size: 15 kDa

false

Western blot - Anti-Hemoglobin antibody (AB231584)
  • WB

Supplier Data

Western blot - Anti-Hemoglobin antibody (AB231584)

All lanes:

Western blot - Anti-Hemoglobin antibody (ab231584) at 2 µg/mL

All lanes:

Human liver lysate

Predicted band size: 15 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Dog, Human, Monkey

Applications

WB

applications

Immunogen

Native Full Length Protein corresponding to Rhesus monkey Hemoglobin subunit alpha.

P63108

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>" }, "Dog": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>" }, "Monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant full length protein - Monkey": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-2 µg/mL", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Purification notes
ab231584 was purified by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
Storage buffer
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Hemoglobin also known as Hb or HBB is a protein found in red blood cells. It is a tetramer with a molecular mass of approximately 64.5 kDa composed of two alpha and two beta subunits. This protein is predominantly expressed in erythrocytes where it plays an important role in oxygen transport from the lungs to tissues and facilitates the return of carbon dioxide from tissues to the lungs for exhalation.
Biological function summary

Hemoglobin carries oxygen in blood and acts as a buffer in maintaining blood pH. Within the erythrocytes hemoglobin comprises one of the principal components of these cells each molecule binding up to four oxygen molecules. Hemoglobin exists as a complex with heme groups that directly interact with oxygen allowing hemoglobin to perform its respiratory function efficiently.

Pathways

Hemoglobin is important in the circulatory and respiratory pathways. It works in conjunction with proteins like myoglobin which assists with oxygen storage in muscles and cytochrome c which is important in the electron transport chain. Hemoglobin's function aligns with these pathways to maintain proper oxygen and energy levels throughout the body.

Hemoglobin abnormalities lead to conditions such as sickle cell anemia and thalassemia. Sickle cell anemia involves a mutation in the beta-globin gene resulting in deformed red blood cells that hinder oxygen delivery and cause pain due to blockages in blood vessels. Thalassemia results from reduced production of globin chains leading to anemia. These conditions involve aberrations in the hemoglobin or related proteins impacting overall health and requiring clinical management.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

Involved in oxygen transport from the lung to the various peripheral tissues.. Hemopressin. Hemopressin acts as an antagonist peptide of the cannabinoid receptor CNR1 (PubMed : 18077343). Hemopressin-binding efficiently blocks cannabinoid receptor CNR1 and subsequent signaling (PubMed : 18077343).
See full target information HBA1
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

NPJ Parkinson's disease 10:194 PubMed39443520

2024

CRBN modulates synuclein fibrillation via degradation of DNAJB1 in mouse model of Parkinson disease.

Applications

Unspecified application

Species

Unspecified reactive species

Uroos Akber,Jun-Hyung Jung,Heewoong Yoon,Jiwon Seo,Chul-Seung Park
View all publications
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