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AB316776

Anti-Hepatitis B Virus Surface Antigen antibody [3E7]

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Mouse Recombinant Monoclonal HBSAG antibody. Suitable for I-ELISA and reacts with Recombinant fragment - Hepatitis B virus samples.

View Alternative Names

LHB, Large envelope protein, Large surface protein, Major surface antigen

1 Images
Indirect ELISA - Anti-Hepatitis B Virus Surface Antigen antibody [3E7] (AB316776)
  • I-ELISA

Supplier Data

Indirect ELISA - Anti-Hepatitis B Virus Surface Antigen antibody [3E7] (AB316776)

Indirect ELISA analysis of ab316776 at 2000-0 ng/ml. The Secondary antibody used was Alkaline Phosphatase-conjugated AffiniPure Goat Anti-Mouse IgG (H+L) at 1 : 1000 dilution.

Antigen : HBsAg,ayw Subtype;HBsAg,adw Subtype.

Antigen concentration : 5000 ng/ml

  • Carrier free

    Anti-Hepatitis B Virus Surface Antigen antibody [3E7] - BSA and Azide free

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

3E7

Isotype

IgG1

Carrier free

No

Reacts with

Hepatitis B virus

Applications

I-ELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IELISA" : {"fullname" : "Indirect ELISA", "shortname":"I-ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Hepatitis B virus": { "IELISA-species-checked": "predicted", "IELISA-species-dilution-info": "", "IELISA-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant fragment - Hepatitis B virus": { "IELISA-species-checked": "testedAndGuaranteed", "IELISA-species-dilution-info": "2000 ng/mL", "IELISA-species-notes": "<p></p>", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Transfected cell lysate - Hepatitis B virus": { "IELISA-species-checked": "notRecommended", "IELISA-species-dilution-info": "", "IELISA-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "<p></p>" } } }
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Product details

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Want a custom formulation?
This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com

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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

The Hepatitis B Virus Surface Antigen commonly known as HBsAg is an important structural protein of the Hepatitis B Virus (HBV). This antigen is also referred to as Hep B surf Ab. Designed with a mass of approximately 24 kDa HBsAg is expressed extensively in the liver tissues of individuals infected with Hepatitis B. It represents the major component of the virus's envelope and plays a role in the formation of subviral particles. Several commercial antibodies such as Hepatitis antibodies and HBV antibodies target HBsAg for analytical and diagnostic purposes in laboratories.
Biological function summary

The Hepatitis B Virus Surface Antigen interacts with the host's immune system and assists in viral replication. HBsAg is not part of a larger protein complex. Rather it circulates as free particles known as 3e-7 and 3e-7 Hepatitis B antigens which are abundant in the blood serum during active infection. These particles act as decoys distracting the host's immune defense and facilitating the persistence of the infection. The production and clearance of HBsAg serve as important indicators of HBV infection status and disease progression.

Pathways

Hepatitis B Virus Surface Antigen plays an integral role in the HBV life cycle particularly within the viral entry and replication pathways. It shares a functional relationship with the HB5 protein which is important for viral particle assembly and release. The interactions between HBsAg and host proteins influence viral propagation and subsequently the overall pathway of HBV infection within hepatocytes. Understanding these interactions can aid in the development of therapeutic interventions to disrupt the viral lifecycle.

Hepatitis B Virus Surface Antigen is directly associated with chronic Hepatitis B infection and hepatocellular carcinoma. Chronic Hepatitis B characterized by the prolonged presence of HBsAg can advance to liver cirrhosis and cancer if untreated. The antigen's persistence is often monitored alongside liver enzymes and other markers such as Hepatitis B antibodies (Hep B antibodies) to assess disease progression and treatment efficacy. Effective management of HBsAg levels helps mitigate the risk and severity of these severe liver diseases.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Hepatitis B Virus Surface Antigen
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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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