Anti-Hepatitis C Virus Core 1b antibody [C7-50]
4
(3 Reviews)
|
(99 Publications)
Reactivity data
Properties and storage information
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Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The Hepatitis C Virus Core Protein influences various cellular processes. It interacts with host cell signaling pathways and cellular structures to facilitate viral replication. As part of a larger proteins complex the core protein contributes to the production of virus particles. Moreover it possesses regulatory roles that impact gene transcription and modulation of host cell immune responses further aiding viral propagation and persistence within the host.
Pathways
Studies show that HCV Core Protein is involved in disrupting normal cellular pathways such as the PI3K-Akt pathway which is significant for cell survival and anti-apoptosis mechanisms. It interacts with proteins like p53 and Bcl-2 which further link to the JAK-STAT pathway involved in immune modulation. These interactions illustrate how the core protein manipulates host cell environments to benefit viral survival and replication while potentially triggering pathogenic pathways within the host.
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Publications (99)
Recent publications for all applications. Explore the full list and refine your search
International journal of biological sciences 21:802-822 PubMed39781468
2025
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Autophagy 20:2238-2254 PubMed38842055
2024
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Acta pharmaceutica Sinica. B 14:2520-2536 PubMed38828143
2024
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PloS one 19:e0303265 PubMed38739590
2024
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Nature communications 15:652 PubMed38253527
2024
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PLoS pathogens 19:e1011552 PubMed37540723
2023
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Avicenna journal of medical biotechnology 15:173-179 PubMed37538239
2023
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Frontiers in immunology 13:1007718 PubMed36532074
2022
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Virology journal 19:118 PubMed35836293
2022
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Virologica Sinica 37:408-417 PubMed35523417
2022
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Product promise
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