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AB1037

Anti-Hepatitis G Virus antibody

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(1 Publication)

Rabbit Polyclonal Hepatitis G Virus antibody. Suitable for WB and reacts with GB virus C samples. Cited in 1 publication.

View Alternative Names

HGV, Hepatitis GB virus C

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

Unknown

Light chain type

unknown

Carrier free

No

Reacts with

GB virus C

Applications

WB

applications

Specificity

This antibody recognizes the NS5 polyprotein of HGV, also known as GBV-C/HBV.

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Primary Antibodies

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Primary Antibodies

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Proteins & Peptides

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "GB virus C": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
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Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.05% Sodium azide
Shipped at conditions
Blue Ice
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle
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Supplementary information

This supplementary information is collated from multiple sources and compiled automatically.

Hepatitis G Virus (HGV) also known as GBV-C is a flavivirus with a single-stranded RNA genome. It has a genome mass of approximately 9.3 kilobases. HGV primarily targets liver tissue and can be expressed in peripheral blood mononuclear cells. The virus belongs to the Flaviviridae family and shares similarities with other hepatitis viruses such as Hepatitis C virus (HCV) but with distinct genetic properties that set it apart in its mechanical structure and infectious process.
Biological function summary

HGV functions through interactions with various cellular receptors and proteins to establish infection in the host. It does not form part of a well-defined protein complex itself but influences the host’s immune response. HGV is known for its potential modulatory effects on the immune system which might inhibit the replication of other viruses especially in co-infection scenarios.

Pathways

Scientists have identified that mechanisms of HGV can impact immune signaling pathways. One important pathway is the inhibition of HIV replication where HGV might interact with cellular proteins to modulate immune responses. HGV's potential relationship with immunomodulatory proteins suggests it might affect pathways similar to those influenced by immune checkpoints or cytokine signaling.

HGV is associated with chronic hepatitis infections although it is less pathogenic compared to other hepatitis viruses. Some studies suggest a correlation between HGV infection and a reduced progression of HIV in co-infected individuals. During co-infection proteins from HGV and HIV could engage in interactions that might slow HIV disease progression presenting a unique area for therapeutic exploration.
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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:
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Target data

See full target information Hepatitis G Virus
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Publications (1)

Recent publications for all applications. Explore the full list and refine your search

Disease models & mechanisms 7:987-96 PubMed25056700

2014

TGF-β mediates early angiogenesis and latent fibrosis in an Emilin1-deficient mouse model of aortic valve disease.

Applications

Unspecified application

Species

Unspecified reactive species

Charu Munjal,Amy M Opoka,Hanna Osinska,Jeanne F James,Giorgio M Bressan,Robert B Hinton
View all publications
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Product promise

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