Mouse Monoclonal Hepatocyte Specific Antigen antibody. Suitable for ICC, ICC/IF, IHC-Fr and reacts with Human samples. Immunogen corresponding to Cell preparation containing Hepatocyte Specific Antigen protein.
pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA
| ICC | ICC/IF | IHC-Fr | |
|---|---|---|---|
| Human | Expected | Expected | Expected |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes Use Acetone fixed cells. |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info Use at an assay dependent concentration. | Notes - |
| Species | Dilution info | Notes |
|---|---|---|
Species Human | Dilution info - | Notes (for 30 minutes at RT). |
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Mouse Monoclonal Hepatocyte Specific Antigen antibody. Suitable for ICC, ICC/IF, IHC-Fr and reacts with Human samples. Immunogen corresponding to Cell preparation containing Hepatocyte Specific Antigen protein.
pH: 7.2 - 7.4
Preservative: 0.05% Sodium azide
Constituents: PBS, 0.05% BSA
ab191200 binds to human hepatocytes and the majority of human hepatocellular carcinomas (HCC’s). The antibody detects a target on the Cell surface of hepatocytes.
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The Hepatocyte Specific Antigen also known as OCH1E5 functions as an important identifier of hepatocytes. This antigen with a mass around 66 kDa is expressed significantly in liver tissues. Researchers often use it as a hepatocyte marker in studies and experiments facilitating the recognition and analysis of liver cells. Its specificity makes it a useful tool in hepatocyte flow cytometry and in histological investigations where defining cell type is important.
The Hepatocyte Specific Antigen participates in the maintenance and function of liver cells. It does not belong to a known complex itself but plays a role in the structural and functional characterization of hepatocytes. These cells' proper function is essential for metabolic processes detoxification and production of vital proteins. Recognizing hepatocyte markers aids in understanding liver health and disease states.
The Hepatocyte Specific Antigen is pivotal for identifying hepatocyte involvement in metabolic pathways such as bile acid biosynthesis and glycolysis. Its presence helps delineate pathways that include proteins like Albumin and Cytochrome P450 both critically involved in liver-specific functions. These pathways highlight the liver's key roles in metabolism and detoxification informed by precise cellular identification.
Hepatocyte Specific Antigen serves as a focal point in studying liver diseases such as hepatitis and liver cirrhosis. Its role in these diseases involves connections with proteins like ALT (Alanine Transaminase) and AST (Aspartate Transaminase) which are often elevated in liver damage. Identifying hepatocyte markers allows researchers to explore disease mechanisms progression and treatment responses enhancing our understanding of liver-specific pathologies.
We have tested this species and application combination and it works. It is covered by our product promise.
We have not tested this specific species and application combination in-house, but expect it will work. It is covered by our product promise.
This species and application combination has not been tested, but we predict it will work based on strong homology. However, this combination is not covered by our product promise.
We do not recommend this combination. It is not covered by our product promise.
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