JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB218417

Anti-Histone H1 antibody [r1415-1]

Be the first to review this product! Submit a review

|

(2 Publications)

Mouse Recombinant Monoclonal H1 antibody. Suitable for Flow Cyt, ICC/IF, IHC-P and reacts with Human, Rat samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human H1-8.

View Alternative Names

H1FOO, H1OO, OSH1, H1-8, Histone H1.8, Histone H1oo, Oocyte-specific histone H1, Oocyte-specific linker histone H1, osH1

4 Images
Immunocytochemistry/ Immunofluorescence - Anti-Histone H1 antibody [r1415-1] (AB218417)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Histone H1 antibody [r1415-1] (AB218417)

Immunocytochemistry analysis of PFA-fixed HeLa (human epithelial cell line from cervix adenocarcinoma) cells labeling Histone H1 with ab218417 followed by goat anti-Mouse IgG-CF488 (Green). Phalloidin (Red) is used to label cell membrane.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Histone H1 antibody [r1415-1] (AB218417)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Histone H1 antibody [r1415-1] (AB218417)

Immunohistochemical analysis of formalin fixed, paraffin embedded Human tonsil tissue labeling Histone H1 using ab218417 at 1 μg/ml.

Flow Cytometry - Anti-Histone H1 antibody [r1415-1] (AB218417)
  • Flow Cyt

Supplier Data

Flow Cytometry - Anti-Histone H1 antibody [r1415-1] (AB218417)

Flow Cytometry analysis of HeLa (human epithelial cell line from cervix adenocarcinoma) cells labeling Histone H1 with ab218417 followed by goat anti-mouse IgG-CF488 (Blue); Isotype Control (Red).

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Histone H1 antibody [r1415-1] (AB218417)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Histone H1 antibody [r1415-1] (AB218417)

Immunohistochemical analysis of formalin fixed, paraffin embedded rat pancreas tissue labeling Histone H1 using ab218417 at 1 μg/ml.

Key facts

Host species

Mouse

Clonality

Monoclonal

Clone number

r1415-1

Isotype

IgG2a

Light chain type

kappa

Carrier free

No

Reacts with

Rat, Human

Applications

IHC-P, ICC/IF, Flow Cyt

applications

Immunogen

Recombinant Full Length Protein corresponding to Human H1-8.

Q8IZA3

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1-2 µg for 10^6 Cells", "FlowCyt-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1-2 µg/mL", "ICCIF-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." }, "Mouse": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol." } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Protein A/G
Storage buffer
pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling (By similarity).
See full target information H1-8

Publications (2)

Recent publications for all applications. Explore the full list and refine your search

Biomedical reports 23:111 PubMed40386306

2025

Notch signaling pathway regulates the progression of fetal growth restriction through mediating immune dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Liyan Ye,Xiujuan Zheng,Yali Yang,Ying Lyu

Journal of virology 96:e0101122 PubMed36094316

2022

HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA.

Applications

Unspecified application

Species

Unspecified reactive species

Nicklas Sapp,Nathaniel Burge,Khan Cox,Prem Prakash,Muthukumar Balasubramaniam,Santosh Thapa,Devin Christensen,Min Li,Jared Linderberger,Mamuka Kvaratskhelia,Jui Pandhare,Robert Craigie,Michael G Poirier,Chandravanu Dash
View all publications

Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.
For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com