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AB240616

Anti-Histone H2B (beta-hydroxybutyryl K11) antibody

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Rabbit Polyclonal H2B beta-hydroxybutyryl K11 antibody. Suitable for WB and reacts with Human samples. Immunogen corresponding to Synthetic Peptide within Human H2BC4 beta-hydroxybutyryl K11.

View Alternative Names

H2BFL, HIST1H2BC, H2BC6, H2BFH, HIST1H2BE, H2BC7, H2BFG, HIST1H2BF, H2BC8, H2BFA, HIST1H2BG, H2BC10, H2BFK, HIST1H2BI, H2BC4, Histone H2B type 1-C/E/F/G/I, Histone H2B.1 A, Histone H2B.a, Histone H2B.g, Histone H2B.h, Histone H2B.k, Histone H2B.l, H2B/a, H2B/g, H2B/h, H2B/k, H2B/l, H2BK11bhb

1 Images
Western blot - Anti-Histone H2B (beta-hydroxybutyryl K11) antibody (AB240616)
  • WB

Supplier Data

Western blot - Anti-Histone H2B (beta-hydroxybutyryl K11) antibody (AB240616)

All lanes:

Western blot - Anti-Histone H2B (beta-hydroxybutyryl K11) antibody (ab240616) at 1/100 dilution

Lane 1:

HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate, treated (+) with 50mM Sodium 3-hydroxybutyrate for 72 hours

Lane 2:

HEK-293 (human epithelial cell line from embryonic kidney) whole cell lysate, treated (+) with 50mM Sodium 3-hydroxybutyrate for 72 hours

Lane 3:

A549 (human lung carcinoma cell line) whole cell lysate, treated (+) with 50mM Sodium 3-hydroxybutyrate for 72 hours

Lane 4:

K562 (human chronic myelogenous leukemia cell line from bone marrow) whole cell lysate, treated (+) with 50mM Sodium 3-hydroxybutyrate for 72 hours

Lane 5:

HeLa whole cell lysate, untreated

Lane 6:

HEK-293 whole cell lysate, untreated

Lane 7:

A549 whole cell lysate, untreated

Lane 8:

K562 whole cell lysate, untreated

Secondary

All lanes:

Goat polyclonal to rabbit IgG at 1/50000 dilution

Predicted band size: 14 kDa

false

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human H2BC4 beta-hydroxybutyryl K11. The exact immunogen used to generate this antibody is proprietary information.

P62807

Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/100.00000 - 1/1000.00000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

Properties and storage information

Form
Liquid
Purification technique
Affinity purification Immunogen
Storage buffer
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
Shipped at conditions
Blue Ice
Appropriate short-term storage duration
1-2 weeks
Appropriate short-term storage conditions
+4°C
Appropriate long-term storage conditions
-20°C
Aliquoting information
Upon delivery aliquot
Storage information
Avoid freeze / thaw cycle

Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Target data

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.. Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
See full target information H2BC4 beta-hydroxybutyryl K11

Product promise

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