AB81797

Anti-Histone H4 (citrulline R3) antibody

Name: Anti-Histone H4 (citrulline R3) antibody (ab81797) | Abcam
Brand: Abcam Limited
SKU: AB81797
Price: 555 USD
Availability: InStock
Rating: 2 (1 reviews)

(1 Review)

(14 Publications)

Rabbit Polyclonal Histone H4 citrulline R3 antibody. Suitable for ELISA, WB, IHC-P and reacts with Synthetic peptide - Human, Human samples. Cited in 14 publications. Immunogen corresponding to Synthetic Peptide within Human H4C1 citR3.

View Alternative Names

H4/A, H4FA, HIST1H4A, H4C2, H4/I, H4FI, HIST1H4B, H4C3, H4/G, H4FG, HIST1H4C, H4C4, H4/B, H4FB, HIST1H4D, H4C5, H4/J, H4FJ, HIST1H4E, H4C6, H4/C, H4FC, HIST1H4F, H4C8, H4/H, H4FH, HIST1H4H, H4C9, H4/M, H4FM, HIST1H4I, H4C11, H4/E, H4FE, HIST1H4J, H4C12, H4/D, H4FD, HIST1H4K, H4C13, H4/K, H4FK, HIST1H4L, H4C14, H4/N, H4F2, H4FN, HIST2H4, HIST2H4A, H4C15, H4/O, H4FO, HIST2H4B, H4C16, H4-16, HIST4H4, H4C1, Histone H4, H4R3cit

1 Images

ELISA - Anti-Histone H4 (citrulline R3) antibody (AB81797)

ELISA

Unknown

ELISA - Anti-Histone H4 (citrulline R3) antibody (AB81797)

ELISA control of the specificity of ab81797 using H4-3cit peptide, H4-Arg3 peptide and H3-cit2, 8, 17 peptide.

Key facts

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ELISA, WB, IHC-P

applications

Immunogen

Synthetic Peptide within Human H4C1 citR3. The exact immunogen used to generate this antibody is proprietary information.

P62805

Specificity

This antibody reacts specifically with human Histone H4 Citrulline at position 3 (10kDa). The antibody does not cross react with free H4 nor with other citrullinated proteins.

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Reactivity data

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ELISA-species-checked": "predicted", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Synthetic peptide - Human": { "ELISA-species-checked": "testedAndGuaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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Properties and storage information

Form

Liquid

Purity

Whole antiserum

Storage buffer

Constituents: Whole serum

Shipped at conditions

Blue Ice

Appropriate short-term storage conditions

+4°C

Appropriate long-term storage conditions

-20°C

Aliquoting information

Upon delivery aliquot

Storage information

Avoid freeze / thaw cycle

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Product protocols

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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Target data

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

See full target information H4C1 citR3

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Publications (14)

Recent publications for all applications. Explore the full list and refine your search

Frontiers in pharmacology 15:1465776 PubMed39734403

2024

Attenuation of neutrophil adhesion and formation of neutrophil extracellular traps by pooled human immune globulins.

Applications

Unspecified application

Species

Unspecified reactive species

Vidhya R Rao,Sana Iqbal,Bradford A Young,Christine Mun,Sandeep Jain,Simon Kaja

International journal of molecular sciences 24: PubMed37686001

2023

Endothelial Damage, Neutrophil Extracellular Traps and Platelet Activation in COVID-19 vs. Community-Acquired Pneumonia: A Case-Control Study.

Applications

Unspecified application

Species

Unspecified reactive species

Paula González-Jiménez,Raúl Méndez,Ana Latorre,Noé Mengot,Mónica Piqueras,Soledad Reyes,Antonio Moscardó,Ricardo Alonso,Isabel Amara-Elori,Rosario Menéndez

Life science alliance 6: PubMed37500179

2023

Inhibition of protein arginine deiminase 4 prevents inflammation-mediated heart failure in arthritis.

Applications

Unspecified application

Species

Unspecified reactive species

Lukas A Heger,Nicolas Schommer,Shoichi Fukui,Stijn Van Bruggen,Casey E Sheehy,Long Chu,Sridharan Rajagopal,Dhanalakshmi Sivanandhan,Bruce Ewenstein,Denisa D Wagner

International journal of molecular sciences 24: PubMed37047662

2023

Neutrophil Extracellular Traps and Platelet Activation for Identifying Severe Episodes and Clinical Trajectories in COVID-19.

Applications

Unspecified application

Species

Unspecified reactive species

Paula González-Jiménez,Raúl Méndez,Ana Latorre,Mónica Piqueras,María Nieves Balaguer-Cartagena,Antonio Moscardó,Ricardo Alonso,David Hervás,Soledad Reyes,Rosario Menéndez

Cells 11: PubMed36497044

2022

SARS-CoV-2-Associated ssRNAs Activate Human Neutrophils in a TLR8-Dependent Fashion.

Applications

Unspecified application

Species

Unspecified reactive species

Elisa Gardiman,Francisco Bianchetto-Aguilera,Sara Gasperini,Laura Tiberio,Matteo Scandola,Virginia Lotti,Davide Gibellini,Valentina Salvi,Daniela Bosisio,Marco A Cassatella,Nicola Tamassia

International journal of molecular sciences 23: PubMed35563373

2022

The PDE4 Inhibitor Tanimilast Restrains the Tissue-Damaging Properties of Human Neutrophils.

Applications

Unspecified application

Species

Unspecified reactive species

Tiziana Schioppa,Hoang Oanh Nguyen,Valentina Salvi,Norma Maugeri,Fabrizio Facchinetti,Gino Villetti,Maurizio Civelli,Carolina Gaudenzi,Mauro Passari,Francesca Sozio,Ilaria Barbazza,Nicola Tamassia,Marco A Cassatella,Annalisa Del Prete,Daniela Bosisio,Laura Tiberio

Frontiers in cardiovascular medicine 8:683445 PubMed35242817

2022

Diagnostic and Prognostic Value of Neutrophil Extracellular Trap Levels in Patients With Acute Aortic Dissection.

Applications

Unspecified application

Species

Unspecified reactive species

Shuofei Yang,Yongsheng Xiao,Yuanfeng Du,Jiaquan Chen,Qihong Ni,Xiangjiang Guo,Guanhua Xue,Xupin Xie

Frontiers in immunology 12:675315 PubMed34616390

2021

Early and Late Processes Driving NET Formation, and the Autocrine/Paracrine Role of Endogenous RAGE Ligands.

Applications

Unspecified application

Species

Unspecified reactive species

Olga Tatsiy,Vanessa de Carvalho Oliveira,Hugo Tshivuadi Mosha,Patrick P McDonald

Arthritis & rheumatology (Hoboken, N.J.) 74:318-328 PubMed34279048

2021

Platelet Phagocytosis via P-selectin Glycoprotein Ligand 1 and Accumulation of Microparticles in Systemic Sclerosis.

Applications

Unspecified application

Species

Unspecified reactive species

Angelo A Manfredi,Giuseppe A Ramirez,Cosmo Godino,Annalisa Capobianco,Antonella Monno,Stefano Franchini,Enrico Tombetti,Sara Corradetti,Jörg H W Distler,Marco E Bianchi,Patrizia Rovere-Querini,Norma Maugeri

PLoS neglected tropical diseases 11:e0005279 PubMed28045905

2017

Human Leukocytes Kill Brugia malayi Microfilariae Independently of DNA-Based Extracellular Trap Release.

Applications

Unspecified application

Species

Unspecified reactive species

Ciaran J McCoy,Barbara J Reaves,Steeve Giguère,Ruby Coates,Balázs Rada,Adrian J Wolstenholme

View all publications

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Product promise

We are committed to supporting your work with high-quality reagents, and we're here for you every step of the way. In the unlikely event that one of our products does not perform as expected, you're protected by our Product Promise.

For full details, please see our Terms & Conditions

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Histone H4 (citrulline R3) antibody

ELISA - Anti-Histone H4 (citrulline R3) antibody (AB81797)

Key facts

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

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Reactivity data

Properties and storage information

Form

Purity

Storage buffer

Shipped at conditions

Appropriate short-term storage conditions

Appropriate long-term storage conditions

Aliquoting information

Storage information

Product protocols

Target data

Publications (14)

Product promise