Rabbit Polyclonal HNRNPUL2 antibody. Suitable for IP, WB and reacts with Human, Mouse samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human HNRNPUL2 aa 1-100.
View Alternative Names
HNRPUL2, HNRNPUL2, Heterogeneous nuclear ribonucleoprotein U-like protein 2, Scaffold-attachment factor A2, SAF-A2
- IP
Supplier Data
Immunoprecipitation - Anti-HNRNPUL2 antibody (AB195338)
Detection of HNRNPUL2 in Immunoprecipitates of 293T whole cell lysates prepared using NETN lysis buffer (1 mg for IP, 20% of IP loaded) using ab195338 at 6 μg per reaction for IP and at 0.1 μg/ml for subsequent Western blot detection.
Detection : Chemiluminescence with an exposure time of 10 seconds.
All lanes:
Immunoprecipitation - Anti-HNRNPUL2 antibody (ab195338)
Predicted band size: 85 kDa
false
- WB
Supplier Data
Western blot - Anti-HNRNPUL2 antibody (AB195338)
All lanes:
Western blot - Anti-HNRNPUL2 antibody (ab195338) at 0.1 µg/mL
Lane 1:
HeLa whole cell lysate prepared using NETN lysis buffer at 50 µg
Lane 2:
293T whole cell lysate prepared using NETN lysis buffer at 50 µg
Lane 3:
Jurkat whole cell lysate prepared using NETN lysis buffer at 50 µg
Lane 4:
Mouse TCMK-1 whole cell lysate prepared using NETN lysis buffer at 50 µg
Lane 5:
Mouse NIH/3T3 whole cell lysate prepared using NETN lysis buffer at 50 µg
Predicted band size: 85 kDa
true
Exposure time: 30s
Reactivity data
Properties and storage information
Form
Purification technique
Storage buffer
Shipped at conditions
Appropriate short-term storage duration
Appropriate short-term storage conditions
Appropriate long-term storage conditions
Aliquoting information
Storage information
Supplementary information
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
HNRNPUL2 functions within the context of ribonucleoprotein complexes specifically linking with nascent RNA transcripts and directing their maturation. It assists in the orchestration of RNA transport to regions necessitating protein synthesis. Additionally it supports the nuclear retention of defective RNA preventing erroneous protein production. By functioning within these complexes it influences gene expression regulatory networks and modulates cellular response to stress.
Pathways
HNRNPUL2's activity integrates within major RNA processing pathways notably in mRNA splicing and export. These pathways facilitate the transition of RNA from the nucleus to the cytoplasm. It often interacts with other RNA-binding proteins such as HNRNPU and NXF1 to ensure mRNA transition is efficient. Through these interactions HNRNPUL2 coordinates the communication between splicing machinery and mRNA export systems securing the fidelity of gene expression.
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Target data
Publications (2)
Recent publications for all applications. Explore the full list and refine your search
eLife 12: PubMed37010886
2023
Applications
Unspecified application
Species
Unspecified reactive species
European journal of histochemistry : EJH 65: PubMed34538046
2021
Applications
Unspecified application
Species
Unspecified reactive species
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